WEKO3
アイテム
{"_buckets": {"deposit": "7704797e-f327-475a-9c19-bb1897e70648"}, "_deposit": {"id": "10352", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10352"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00010352", "sets": ["1017"]}, "author_link": ["32755", "32756", "32757", "32758"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-10-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "15", "bibliographicPageStart": "11", "bibliographicVolumeNumber": "65", "bibliographic_titles": [{"bibliographic_title": "MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL"}]}]}, "item_6_description_20": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Five-week-old male mice were divided into 2 groups in which they were orally given sterile saline solution (control solution) or cow\u0027s colostrum powder prepared from milk produced 6 to 7 days after parturition in sterile saline solution (colostrum solution). The mice were given the solution once a day for 5 weeks. The level of intestinal total IgG was significantly lower in the mice given the colostrum solution than in the mice given the control solution, and the intestinal IgA and serum IgG levels tended to be lower in the mice given the colostrum solution. The numbers of spleen CD11b(+), CD19(+), and IFN-gamma(+)CD4(+) cells were also significantly lower in mice given the colostrum solution. DNA microarray analysis of mRNAs extracted from Peyer\u0027s patch cells showed that the gene expression of proteins relating to T cell activation of acquired immune responses or Fc epsilon-mediated mast cell activation was obviously lower in the mice given the colostrum solution than in the mice given the control solution, whereas that of proteins relating to T regulatory cells or intestinal innate immune system was noticeably higher in mice given the colostrum solution. These results suggest that the oral ingestion of cow\u0027s colostrum suppresses the acquired immune system and type I allergic reactions, and enhances the innate immune system.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "資源タイプ(コンテンツの種類)", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "フォーマット:mimeタイプ", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL. 65(1):11-15 (2010)", "subitem_description_type": "Other"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000274083500004"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "A V A AGRARVERLAG"}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0026-3788", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0026-3788", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00285427", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "Colostrum (mouse immune system)"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "CASEIN PHOSPHOPEPTIDE PREPARATION; MILK IMMUNOGLOBULIN-G; INFLAMMATORY RESPONSE; CELL-ACTIVATION; EXPRESSION; MICE; LYMPHOCYTES; RECEPTOR; ROLES; ALPHA"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Five-week-old male mice were divided into 2 groups in which they were orally given sterile saline solution (control solution) or cow\u0027s colostrum powder prepared from milk produced 6 to 7 days after parturition in sterile saline solution (colostrum solution). The mice were given the solution once a day for 5 weeks. The level of intestinal total IgG was significantly lower in the mice given the colostrum solution than in the mice given the control solution, and the intestinal IgA and serum IgG levels tended to be lower in the mice given the colostrum solution. The numbers of spleen CD11b(+), CD19(+), and IFN-gamma(+)CD4(+) cells were also significantly lower in mice given the colostrum solution. DNA microarray analysis of mRNAs extracted from Peyer\u0027s patch cells showed that the gene expression of proteins relating to T cell activation of acquired immune responses or Fc epsilon-mediated mast cell activation was obviously lower in the mice given the colostrum solution than in the mice given the control solution, whereas that of proteins relating to T regulatory cells or intestinal innate immune system was noticeably higher in mice given the colostrum solution. These results suggest that the oral ingestion of cow\u0027s colostrum suppresses the acquired immune system and type I allergic reactions, and enhances the innate immune system."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ohashi, Yuki"}], "nameIdentifiers": [{"nameIdentifier": "32755", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uchida, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "32756", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawasaki, Mihoko"}], "nameIdentifiers": [{"nameIdentifier": "32757", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Otani, Hajime"}], "nameIdentifiers": [{"nameIdentifier": "32758", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "effect_mouse_immune_ system.pdf", "filesize": [{"value": "5.7 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 5700000.0, "url": {"label": "effect_mouse_immune_ system.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/10352/files/effect_mouse_immune_ system.pdf"}, "version_id": "f6b429ea-b5e0-4ae3-84ab-afcce75d2058"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Colostrum (mouse immune system)", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The effect on mouse immune systems of cow\u0027s colostrum produced 6 to 7 days after parturition", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The effect on mouse immune systems of cow\u0027s colostrum produced 6 to 7 days after parturition", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1017"], "permalink_uri": "http://hdl.handle.net/10091/10764", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2010-11-15"}, "publish_date": "2010-11-15", "publish_status": "0", "recid": "10352", "relation": {}, "relation_version_is_last": true, "title": ["The effect on mouse immune systems of cow\u0027s colostrum produced 6 to 7 days after parturition"], "weko_shared_id": -1}
The effect on mouse immune systems of cow's colostrum produced 6 to 7 days after parturition
http://hdl.handle.net/10091/10764
http://hdl.handle.net/10091/10764e9e6fa64-3d8b-4324-805c-5e74b5bd58ac
名前 / ファイル | ライセンス | アクション |
---|---|---|
effect_mouse_immune_ system.pdf (5.7 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2010-11-15 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The effect on mouse immune systems of cow's colostrum produced 6 to 7 days after parturition | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | Colostrum (mouse immune system) | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Ohashi, Yuki
× Ohashi, Yuki× Uchida, Kenji× Kawasaki, Mihoko× Otani, Hajime |
|||||
出版者 | ||||||
出版者 | A V A AGRARVERLAG | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL. 65(1):11-15 (2010) | |||||
書誌情報 |
MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL 巻 65, 号 1, p. 11-15, 発行日 2010-10-02 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Five-week-old male mice were divided into 2 groups in which they were orally given sterile saline solution (control solution) or cow's colostrum powder prepared from milk produced 6 to 7 days after parturition in sterile saline solution (colostrum solution). The mice were given the solution once a day for 5 weeks. The level of intestinal total IgG was significantly lower in the mice given the colostrum solution than in the mice given the control solution, and the intestinal IgA and serum IgG levels tended to be lower in the mice given the colostrum solution. The numbers of spleen CD11b(+), CD19(+), and IFN-gamma(+)CD4(+) cells were also significantly lower in mice given the colostrum solution. DNA microarray analysis of mRNAs extracted from Peyer's patch cells showed that the gene expression of proteins relating to T cell activation of acquired immune responses or Fc epsilon-mediated mast cell activation was obviously lower in the mice given the colostrum solution than in the mice given the control solution, whereas that of proteins relating to T regulatory cells or intestinal innate immune system was noticeably higher in mice given the colostrum solution. These results suggest that the oral ingestion of cow's colostrum suppresses the acquired immune system and type I allergic reactions, and enhances the innate immune system. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0026-3788 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00285427 | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000274083500004 |