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A total of 50 mutations with a genome-wide distribution were identified and characterized for mutational types and mutagenic specificities. Those mutations were all point mutations with single-base substitutions and no deletions, frame shifts, and insertions were found. Among six possible types of base substitutions, the mutations consisted of only two types: 47 G.C --\u003e A.T transitions and three A.T --\u003e G.C transitions with no transversion. The findings indicate a limited repertoire of amino acid substitutions by classical NTG multagenesis and thus raise a new possibility of further improving industrial strains by optimizing key mutations through PCR-mediated site-directed mutagenesis. (C) 2007 Elsevier B.V. All rights reserved."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ohnishi, J"}], "nameIdentifiers": [{"nameIdentifier": "32956", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizoguchi, H"}], "nameIdentifiers": [{"nameIdentifier": "32957", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takeno, S"}], "nameIdentifiers": [{"nameIdentifier": "32958", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ikeda, M"}], "nameIdentifiers": [{"nameIdentifier": "32959", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "mutation_research.pdf", "filesize": [{"value": "151.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 151600.0, "url": {"label": "mutation_research.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/10419/files/mutation_research.pdf"}, "version_id": "a8d0ee84-268b-4057-bbc4-87616d0ac244"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Characterization of mutations induced by N-methyl-N \u0027-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Characterization of mutations induced by N-methyl-N \u0027-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1017"], "permalink_uri": "http://hdl.handle.net/10091/1015", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-03-31"}, "publish_date": "2008-03-31", "publish_status": "0", "recid": "10419", "relation": {}, "relation_version_is_last": true, "title": ["Characterization of mutations induced by N-methyl-N \u0027-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain"], "weko_shared_id": -1}
Characterization of mutations induced by N-methyl-N '-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain
http://hdl.handle.net/10091/1015
http://hdl.handle.net/10091/101554732719-0c65-4ce8-aef9-1e0a5de73feb
名前 / ファイル | ライセンス | アクション |
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mutation_research.pdf (151.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-03-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Characterization of mutations induced by N-methyl-N '-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Ohnishi, J
× Ohnishi, J× Mizoguchi, H× Takeno, S× Ikeda, M |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Takeno, S | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HULePUkh.html | |||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Ikeda, M | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.uhLNPUkh.html | |||||
出版者 | ||||||
出版者 | ELSEVIER SCIENCE BV | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS. 649(1-2): 239-244 (2008) | |||||
書誌情報 |
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 巻 649, 号 1-2, p. 239-244, 発行日 2008-01-08 |
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資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1383-5718 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11116545 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/18037338/ | |||||
関連名称 | 18037338 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.mrgentox.2007.10.003 | |||||
関連名称 | 10.1016/j.mrgentox.2007.10.003 | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000252795800025 |