WEKO3
アイテム
{"_buckets": {"deposit": "83cfd5ed-c1ca-4648-af35-6d5a25a5d9fd"}, "_deposit": {"id": "12675", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "12675"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00012675", "sets": ["1222"]}, "author_link": ["38884", "38885", "38886"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2006-11", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "555", "bibliographicPageStart": "539", "bibliographicVolumeNumber": "21", "bibliographic_titles": [{"bibliographic_title": "Journal of Bioactive and Compatible Polymers"}]}]}, "item_6_description_30": {"attribute_name": "資源タイプ(コンテンツの種類)", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "フォーマット:mimeタイプ", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Journal of Bioactive and Compatible Polymers. 21(6): 539-555 (2006)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Okumura, Y", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.gNDVgpAF.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000241631500005"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "SAGE Publications"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1177/0883911506070822"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1177/0883911506070822", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "The final, definitive version of this article has been published in the Journal, Journal of Bioactive and Compatible Polymers. 21(6): 539-555 (2006) © SAGE Publications Ltd, 2006 by SAGE Publications Ltd at the Journal of Bioactive and Compatible Polymers page: http://jbc.sagepub.com/ on SAGE Journals Online: http://online.sagepub.com/"}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0883-9115", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0883-9115", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10698773", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "liposomes; Sephacryl S-1000; disulfide linkages; thiols; FITC-dextran; dithiothreitol; hydrophobized gel"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "UNILAMELLAR LIPOSOMES; PHOSPHOLIPID-VESICLES; MEMBRANE INTERACTIONS; CHROMATOGRAPHY; BEADS; DERIVATIVES; PARTICLES; PROTEINS; SUPPORT"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Immobilization of liposomes onto chemically modified Sephacryl gel particles by in situ reaction between liposome-incorporated thiols and mercapto moieties on the gel to form disulfide linkages was investigated. For the immobilization, both the mercapto moieties and the incorporated thiol were essential. The immobilization occurred upon coincubation of the modified liposomes with the modified gel for 48 hours. Once immobilized, no spontaneous detachment of the immobilized liposomes was observed. The degree of immobilization depended on both the thiol content and the ratio of the liposomes to the gel partilces. In a typical immobilization with 25 mol% 1-octanethiol, 82% of the liposomal phosphatidylcholine in the system was found to be associated with the gel. By decreasing the ratio of the liposomes to gel it was possible to bring the immobilization close to quantitative one. Among the three different thiols examined (1-octanethiol, 1-hexadecanethiol and thiocholesterol), the extent of the immobilization was slightly higher with thiocholesterol. than the alkanethiols. The immobilized liposomes were detached from the gel with dithiothreitol. Approximately 60% of the fluorescent dextran derivative encapsulated in the liposomes was retained throughout the immobilization-detachment process. The gel left after the detachment remained active for immobilizing a fresh batch of thiol-liposomes."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Khaleque, MD. Abdul"}], "nameIdentifiers": [{"nameIdentifier": "38884", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okumura, Y"}], "nameIdentifiers": [{"nameIdentifier": "38885", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mitani, M"}], "nameIdentifiers": [{"nameIdentifier": "38886", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Khaleque_Okumura_Mitani.pdf", "filesize": [{"value": "440.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 440300.0, "url": {"label": "Khaleque_Okumura_Mitani.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/12675/files/Khaleque_Okumura_Mitani.pdf"}, "version_id": "c621a52a-07ce-4e49-921f-75e508937305"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Liposome Immobilization on Cross-linked Polymer Gel by In Situ Formation of Cleavable Covalent Bonds", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Liposome Immobilization on Cross-linked Polymer Gel by In Situ Formation of Cleavable Covalent Bonds", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1222"], "permalink_uri": "http://hdl.handle.net/10091/989", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-02-13"}, "publish_date": "2008-02-13", "publish_status": "0", "recid": "12675", "relation": {}, "relation_version_is_last": true, "title": ["Liposome Immobilization on Cross-linked Polymer Gel by In Situ Formation of Cleavable Covalent Bonds"], "weko_shared_id": -1}
Liposome Immobilization on Cross-linked Polymer Gel by In Situ Formation of Cleavable Covalent Bonds
http://hdl.handle.net/10091/989
http://hdl.handle.net/10091/989b054fca7-28f5-427a-a315-de76b79de8b4
名前 / ファイル | ライセンス | アクション |
---|---|---|
Khaleque_Okumura_Mitani.pdf (440.3 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2008-02-13 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Liposome Immobilization on Cross-linked Polymer Gel by In Situ Formation of Cleavable Covalent Bonds | |||||
言語 | ||||||
言語 | eng | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1177/0883911506070822 | |||||
関連名称 | 10.1177/0883911506070822 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Khaleque, MD. Abdul
× Khaleque, MD. Abdul× Okumura, Y× Mitani, M |
|||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Okumura, Y | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gNDVgpAF.html | |||||
出版者 | ||||||
出版者 | SAGE Publications | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Bioactive and Compatible Polymers. 21(6): 539-555 (2006) | |||||
書誌情報 |
Journal of Bioactive and Compatible Polymers 巻 21, 号 6, p. 539-555, 発行日 2006-11 |
|||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0883-9115 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10698773 | |||||
権利 | ||||||
権利情報 | The final, definitive version of this article has been published in the Journal, Journal of Bioactive and Compatible Polymers. 21(6): 539-555 (2006) © SAGE Publications Ltd, 2006 by SAGE Publications Ltd at the Journal of Bioactive and Compatible Polymers page: http://jbc.sagepub.com/ on SAGE Journals Online: http://online.sagepub.com/ | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000241631500005 |