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Genetic background of autoimmune hepatitis in Japan
http://hdl.handle.net/10091/16882
http://hdl.handle.net/10091/16882b8ef8b26-1955-4085-8fde-6b5e99bd7b22
名前 / ファイル | ライセンス | アクション |
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Genetic_background_autoimmune_hepatitis_Japan.pdf (87.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-04-01 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Genetic background of autoimmune hepatitis in Japan | |||||
言語 | ||||||
言語 | eng | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s00535-010-0333-2 | |||||
関連名称 | 10.1007/s00535-010-0333-2 | |||||
キーワード | ||||||
主題 | Autoimmune hepatitis, Genome-wide association study, Human leukocyte antigen, Single nucleotide polymorphisms, Tumor necrosis factor | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Yoshizawa, Kaname
× Yoshizawa, Kaname× Umemura, Takeji× Ota, Masao |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Umemura, Takeji | |||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html | |||||
信州大学研究者総覧へのリンク | ||||||
氏名 | Ota, Masao | |||||
URL | https://soar-rd.shinshu-u.ac.jp/profile/ja.ZefVOFkh.html | |||||
出版者 | ||||||
出版者 | SPRINGER TOKYO | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF GASTROENTEROLOGY. 46(1):42-47 (2011) | |||||
書誌情報 |
JOURNAL OF GASTROENTEROLOGY 巻 46, 号 1, p. 42-47, 発行日 2011-01 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Autoimmune hepatitis (AIH) is an organ-specific autoimmune disease characterized by chronic inflammation of the liver. Several studies from ethnically different countries have clarified that the genetic predisposition to type 1 AIH is linked mainly to human leukocyte antigen (HLA)-class II genes. Recently, molecular analysis using polymerase chain reaction (PCR)-based DNA typing has revealed that susceptibility to type 1 AIH is primarily associated with the HLA class II DRB1 locus, which encodes a polymorphic beta chain of the HLA-DR antigen. However, additional susceptibility genes (either HLA or non-HLA) and/or environmental factors may also contribute to the development of type 1 AIH; in Japanese type 1 AIH patients, although the most influential gene in disease susceptibility is HLA-DRB1*04:05, several other genes have been identified as being involved in AIH pathogenesis or resistance and are the currently the focus of single nucleotide polymorphism analysis. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0944-1174 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10988015 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/20957499 | |||||
関連名称 | 20957499 | |||||
権利 | ||||||
権利情報 | The final publication is available at www.springerlink.com | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000284646400007 |