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2022-12-14T04:39:58Z
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Basic Potential of Carbon Nanotubes in Tissue Engineering Applications
Haniu, Hisao
Saito, Naoto
Matsuda, Yoshikazu
Tsukahara, Tamotsu
Usui, Yuki
Narita, Nobuyo
Hara, Kazuo
Aoki, Kaoru
Shimizu, Masayuki
Ogihara, Nobuhide
Takanashi, Seiji
Okamoto, Masanori
Kobayashi, Shinsuke
Ishigaki, Norio
Nakamura, Koichi
Kato, Hiroyuki
Copyright © 2012 Hisao Haniu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs) in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.
Article
Journal of Nanomaterials. 2012:34374 (2012)
Hindawi Publishing Corporation
2012
eng
journal article
VoR
http://hdl.handle.net/10091/15727
https://soar-ir.repo.nii.ac.jp/records/3849
https://doi.org/10.1155/2012/343747
10.1155/2012/343747
1687-4110
Journal of Nanomaterials
2012
https://soar-ir.repo.nii.ac.jp/record/3849/files/Basic_Potential_Carbon_Nanotubes_Tissue_Engineering_Applications.pdf
application/pdf
3.2 MB
2015-09-24