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2023-02-27T02:19:46Z
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AIDS とB型肝硬変に合併した原発性滲出性リンパ腫
Primary Effusion Lymphoma Complicated by Hepatitis B Virus-Induced Liver Cirrhosis and Acquired Immunodeficiency Syndrome
清水, 郁夫
北野, 喜良
城下, 智
上條, 敦
高橋, 寧史
矢崎, 善一
松林, 潔
宮林, 秀晴
熊谷, 美恵子
青木, 雄次
古田, 清
市川, 和夫
AIDS
primary effusion lymphoma
hepatitis B cirrhosis
後天性免疫不全症候群
原発性滲出性リンパ腫
B型肝硬変
Primary effusion lymphoma (PEL) is a rare subset of non-Hodgkin’s lymphoma that predominantly grows in body cavities as neoplastic effusions without a contiguous tumor mass. Most PEL cases occur in an immunocompromised state, such as AIDS. We report a case of PEL complicated by not only AIDS but also liver cirrhosis. A 48-year-old man was referred to our hospital because of pleural effusion, ascites and emaciation. Cytologic study and CT revealed the existence of lymphoma cells in the effusion, without mass lesion, leading to a diagnosis of PEL. He was also diagnosed as having AIDS and hepatitis B liver cirrhosis. A large amount of HHV-8 DNA was found in the pleural effusion. Lamivudine and HAART treatment were given for the HBV and HIV infection respectively. Chemotherapies with CHOP, EPOCH, or DeVIC were refractory for PEL, and the patient died of hepatic failure and cerebral hemorrhage. This is the first report of an AIDS patient complicated by PEL and liver cirrhosis.
Article
信州医学雑誌 54(3): 131-136(2006)
信州医学会
2006-06
jpn
journal article
VoR
http://hdl.handle.net/10091/3686
https://soar-ir.repo.nii.ac.jp/records/4240
https://doi.org/10.11441/shinshumedj.54.131
10.11441/shinshumedj.54.132
0037-3826
AN00120815
信州医学雑誌
54
3
131
136
https://soar-ir.repo.nii.ac.jp/record/4240/files/Shinshu_Med54-3-04.pdf
application/pdf
402.1 kB
2015-09-24