2024-03-29T10:50:22Z
https://soar-ir.repo.nii.ac.jp/oai
oai:soar-ir.repo.nii.ac.jp:00010779
2023-01-06T01:11:29Z
1016:1018:1019:1055
The Effect of the Administration of Trace Amounts of Metals to Pregnant Mice upon the Behavior and Learning of Their Offspring
妊娠マウスへの22種の微量の金属投与が子の行動および学習に与える影響
TSUJII, Hirotada
HOSHISHIMA, Keiichiro
The effect of 22 kinds of metals on the response of reflex and behavioral test in suckling mice and on maze learning test of the mature pups was investigated. CFW mice were injected intraperitoneally with trace amounts of metals 11 times during pregnancy. The metals tested were Al, Be, Cd, Co, Cu, F, Fe, Hg, In, La, Mg, Mn, Mo, Ni, Pb, Sb, Sc, Se, Ti, V, Y and Zr. The offspring of mice injected with trace amounts of metals clearly accelerated as to response of straight walking, pivoting, rooting reflex, grasp reflex, crossed extensor and auditory startle in the reflex and behavioral tests. Later on offspring of mice injected with trace amounts of metals were affected so as to influence their maze learning behavior at 5-7 weeks age. This study clearly established that mice from mothers receiving trace amountsof metals during pregnancy produced long lasting behavioral changes from birth to maturity in offspring of both sexes.
Article
信州大学農学部紀要 16(1): 13-28(1979)
信州大学農学部
1979-07-25
eng
departmental bulletin paper
VoR
http://hdl.handle.net/10091/2335
https://soar-ir.repo.nii.ac.jp/records/10779
0583-0621
AN00121352
信州大学農学部紀要
16
1
13
28
https://soar-ir.repo.nii.ac.jp/record/10779/files/Agriculture16-01-02.pdf
application/pdf
823.5 kB
2015-09-25