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Large-scale generation of differentiated cells to achieve regenerative medicine
Sasaki, Katsunori
© Sasaki; licensee BioMed Central Ltd. 2014 / This article is published under license to BioMed Central Ltd. The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The effects of microgravity and fluid dynamic stress on embryoid bodies generated from pluripotent stem cells induce and direct their differentiation. Using this hydrodynamic effect combined with exogenous factors and three-dimensional culture, a new technique has been developed to produce functional, effective, and safe hepatocytes for transplantation. The evolution of this technique will lead to automated production of a large number of differentiated cells and will significantly contribute to regenerative medicine.
Article
STEM CELL RESEARCH & THERAPY. 5:10 (2014)
BIOMED CENTRAL LTD
2014-01-16
eng
journal article
VoR
http://hdl.handle.net/10091/00020103
https://soar-ir.repo.nii.ac.jp/records/19342
https://pubmed.ncbi.nlm.nih.gov/24444304
24444304
https://doi.org/10.1186/scrt399
10.1186/scrt399
1757-6512
STEM CELL RESEARCH & THERAPY
5
10
https://soar-ir.repo.nii.ac.jp/record/19342/files/Large-scale_generation_differentiated_cells.pdf
application/pdf
191.3 kB
2017-12-25