2024-03-28T09:42:33Z
https://soar-ir.repo.nii.ac.jp/oai
oai:soar-ir.repo.nii.ac.jp:00003730
2022-12-14T04:38:30Z
461:462
Disturbed Resting Functional Inter-Hemispherical Connectivity of the Ventral Attentional Network in Alpha Band Is Associated with Unilateral Spatial Neglect
Sasaki, Tsutomu
Abe, Masayuki
Okumura, Eiichi
Okada, Toyoji
Kondo, Kimito
Sekihara, Kensuke
Ide, Wataru
Kamada, Hajime
Unilateral spatial neglect (USN) is one of the most common symptoms of right hemisphere damage; its classical symptom is that patients fail to respond to information on their left side. It has been postulated that disturbance of 2 separate attentional networks relates to the occurrence of USN. However, little is known about the underlying mechanism and neuronal substrates. In this study, we measured spontaneous neural activity by means of magnetoencephalography in 13 patients with brain damage and 5 control subjects. To study the relationship between functional connectivity at rest and severity of USN symptoms, we determined the imaginary coherence values relating to the inter-hemispherical ventral and dorsal attentional networks, as well as the clinical severity of USN using neuropsychological tests and behavioral rating scales. The present results showed that inter-hemispherical connectivity in the ventral attentional network, especially between the left and right angular gyri, detected in the alpha band is associated with the severity of USN symptoms. This may suggest that connectivity of inter-hemispherical homologous regions of the ventral attentional network in the alpha band could be one of the biomarkers of attentional network imbalance occurring in patients with USN.
Article
PLOS ONE. 8(9):e73416 (2013)
journal article
PUBLIC LIBRARY SCIENCE
2013-09-04
application/pdf
PLOS ONE
9
8
e73416
1932-6203
https://soar-ir.repo.nii.ac.jp/record/3730/files/Disturbed_Resting_Functional_Inter-Hemispherical_Connectivity.pdf
eng
24023873
https://pubmed.ncbi.nlm.nih.gov/24023873
10.1371/journal.pone.0073416
https://doi.org/10.1371/journal.pone.0073416
Copyright© 2013 Sasaki et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.