2024-03-28T16:43:53Z
https://soar-ir.repo.nii.ac.jp/oai
oai:soar-ir.repo.nii.ac.jp:00003733
2022-12-14T04:39:35Z
461:462
Surgical outcomes in patients with small cell lung cancer: comparative analysis of computed tomograpy-detected patients with others
Koizumi, Tomonobu
Fukushima, Toshirou
Hamanaka, Kazutoshi
Shiina, Takayuki
Yoshida, Kazuo
Kondo, Ryoichi
Yamamoto, Ryouhei
Nishizawa, Nobuhiro
Small cell lung cancer
Chemotherapy
Surgery
Survey
LD-SCLC
Early stage
Background: It is shown that low-dose computed tomography (CT) screening is useful for a reduction in lung-cancer- specific mortality in heavy smokers. However, the information about effectiveness according to the histological types of lung cancer has not been adequately investigated especially small cell lung cancer (SCLC). The present study was performed to see the clinical benefit of CT screening in patients with SCLC following thoracotomy. Methods: We retrospectively reviewed the outcome in patients with early stage SCLC who initially underwent thoracotomy. The clinical stages and actuarial survival were estimated according to the three means of detection of SCLC: chest CT, radiographic screen, and symptomatically prompted cases. Results: Sixty-nine patients (men/women, 63/6; mean age, 70 years) with SCLC underwent thoracotomy between 1991 and 2010 including chest CT (n = 13), radiographic screening (n = 39), and symptomatically prompted cases (n = 17). Pathological staging information included stage IA (n = 25), IB (n = 8), IIA (n = 13), IIB (n = 5), IIIA (n = 11), and IIIB (n = 7). Median survival time was 30.0 (95% confidence interval (CI): 22.0 to 57.0) months, with overall survival at 5 years of 34.3% (95% CI, 23.47 to 47.3). Nine patients (69%) with stage I were detected by CT which was significantly higher than those in other detection arms. However, there were no significant differences in the survival between CT and other detection arms. Conclusions: CT examination may be useful for detection in early stage SCLC potentially suitable for surgery, but the contribution to better clinical outcome in patients with SCLC remains unclear.
Article
WORLD JOURNAL OF SURGICAL ONCOLOGY. 11:61 (2013)
journal article
BIOMED CENTRAL LTD
2013-03-08
application/pdf
WORLD JOURNAL OF SURGICAL ONCOLOGY
11
61
1477-7819
AA12048269
https://soar-ir.repo.nii.ac.jp/record/3733/files/Surgical_outcomes_patients_small_cell.pdf
eng
23497006
https://pubmed.ncbi.nlm.nih.gov/23497006
10.1186/1477-7819-11-61
https://doi.org/10.1186/1477-7819-11-61
Copyright© 2013 Koizumi et al; licensee BioMed Central Ltd. / This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.