2024-03-28T19:14:46Z
https://soar-ir.repo.nii.ac.jp/oai
oai:soar-ir.repo.nii.ac.jp:00003763
2022-12-14T04:38:28Z
461:462
Isolation of an X-factor-dependent but porphyrin-positive Escherichia coli from urine of a patient with hemorrhagic cystitis
Matsumoto, Takehisa
Kawakami, Yoshiyuki
Sueki, Akane
Kasuga, Eriko
Oana, Kozue
Horiuchi, Kazuki
Kato, Miyuki
Honda, Takayuki
X-factor-dependent
Hemin-requiring
Escherichia coli
Porphyrin test
An Escherichia coli isolate was recovered from a 92-year-old female patient with urinary tract infection. Gram-stained preparation of the urine sediment manifested some gram-negative rod-shaped cells, and the urine specimen culture yielded nonhemolytic colonies on sheep blood agar plate. However, no visible colonies appeared on modified Drigalski agar plate. The isolate was finally identified as an X-factor-dependent E. coli. The interesting finding was that the isolate revealed a positive reaction for porphyrin test despite the requirement of hemin. This finding suggested that some pyrrol-ring-containing porphyrin compounds or fluorescent porphyrins had been produced as chemical intermediates in the synthetic pathway from delta-amino-levulinic acid (ALA), although the isolate should be devoid of synthesizing hems from ALA. This was the first clinical isolation of such a strain, indicating that the E. coli isolate should possess incomplete synthetic pathways of hems from ALA.
Article
JOURNAL OF INFECTION AND CHEMOTHERAPY. 19(4):764-766 (2013)
journal article
SPRINGER JAPAN KK
2013-08
application/pdf
JOURNAL OF INFECTION AND CHEMOTHERAPY
4
19
764
766
1341-321X
AA11057978
https://soar-ir.repo.nii.ac.jp/record/3763/files/Isolation_X-Factor_Dependent_but_Porphyrin_Positive_Escherichiai.pdf
eng
23108428
https://pubmed.ncbi.nlm.nih.gov/23108428
10.1007/s10156-012-0503-7
https://doi.org/10.1007/s10156-012-0503-7
The original publication is available at www.springerlink.com