2024-03-29T09:37:22Z
https://soar-ir.repo.nii.ac.jp/oai
oai:soar-ir.repo.nii.ac.jp:00003794
2022-12-14T03:49:22Z
461:462
Primary ALK-1-negative anaplastic large cell lymphoma of the brain: Case report and review of the literature
Kodama, Kunihiko
Hokama, Masanobu
Kawaguchi, Kenji
Tanaka, Yuichiro
Hongo, Kazuhiro
ALK-1
anaplastic large cell lymphoma
brain
CD30
Anaplastic large cell lymphoma (ALCL) is a type of non-Hodgkin lymphoma composed of CD30-positive cells. Anaplastic lymphoma kinase (ALK) -1 positive ALCL frequently involves both lymph nodes and extranodal sites. While primary extranodal involvement of ALK-1 negative ALCL is rare, this case is unique in that it is a case of primary ALK-1 negative ALCL of the brain. A 79-year-old man presented with dementia-like symptoms. Neuroimaging revealed a well-enhanced mass in the left parieto-occipital region. The tumor was excised and histological diagnosis of primary ALK-1-negative ALCL was made. Primary ALK-1-negative ALCL in this case showed aggressive clinical behavior and fatal outcome. It is of great importance to avoid any delay in reaching an accurate diagnosis, as even primary ALCL of the brain is too seldom suspected clinically.
Article
NEUROPATHOLOGY. 29(2):166-171 (2009)
journal article
WILEY-BLACKWELL PUBLISHING, INC
2009-04
application/pdf
NEUROPATHOLOGY
2
29
166
171
0919-6544
AA11009964
https://soar-ir.repo.nii.ac.jp/record/3794/files/Primary_ALK-1-negative_anaplastic_large_cell_lymphoma.pdf
eng
18564100
https://pubmed.ncbi.nlm.nih.gov/18564100
10.1111/j.1440-1789.2008.00935.x
https://doi.org/10.1111/j.1440-1789.2008.00935.x
Copyright© 2008 Japanese Society of Neuropathology