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        <identifier>oai:soar-ir.repo.nii.ac.jp:00003914</identifier>
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          <dc:title>Effects of mild calorie restriction and high-intensity interval walking in middle-aged and older overweight Japanese</dc:title>
          <dc:creator>Sawashita,  Jinko</dc:creator>
          <dc:creator>Onitsuka,  Sayaka</dc:creator>
          <dc:creator>Gen-no,  Hirokazu</dc:creator>
          <dc:creator>Ishikawa,  Shinobu</dc:creator>
          <dc:creator>Iino,  Fumie</dc:creator>
          <dc:creator>Tateishi,  Norihiko</dc:creator>
          <dc:creator>Murakami,  Takeo</dc:creator>
          <dc:creator>Seki,  Yoichi</dc:creator>
          <dc:creator>Nagaiwa,  Toshiyuki</dc:creator>
          <dc:creator>Hanaoka,  Masaaki</dc:creator>
          <dc:creator>Hama,  Sumio</dc:creator>
          <dc:creator>Nose,  Hiroshi</dc:creator>
          <dc:creator>Higuchi,  Keiichi</dc:creator>
          <dc:subject>BMI</dc:subject>
          <dc:subject>High-intensity interval walking</dc:subject>
          <dc:subject>Hypertension</dc:subject>
          <dc:subject>Medical expenditures</dc:subject>
          <dc:subject>Mild calorie restriction</dc:subject>
          <dc:description>We investigated whether a combination of mild calorie restriction (MCR) and high-intensity interval walking (HIW) improved physical fitness more than HIW alone in middle-aged and older overweight Japanese (40-69 years old, BMI &gt;= 23.6 kg/m(2)). Forty-seven women and 16 men were divided into MCR + HIW and HIW groups. All subjects performed HIW: &gt;= 5 sets of 3-min low-intensity walking (40% peak aerobic capacity for walking, VO2peak) and 3-min high-intensity walking (&gt;= 70% VO2peak) per day, &gt;= 4 days per week, for 16 weeks while energy expenditure was monitored with a tri-axial accelerometer. The MCR + HIW group consumed meal replacement formula (240 kcal): a mixture of low-carbohydrates and -fat and high-protein, for either lunch or dinner everyday and therefore, had similar to 87% of the energy intake of the HIW group during the intervention period. Although the HIW group showed improvements in BMI, blood pressure, and several blood chemicals, the MCR + HIW group had greater improvement. Moreover, the medical expenditure for the 6 months including the intervention period was 59% lower in the MCR + HIW group than in the HIW group. Our strategy of a short-term combination of MCR and HIW may thus prevent lifestyle-associated diseases and improve health in middle-aged and older overweight Japanese.</dc:description>
          <dc:description>Article</dc:description>
          <dc:description>EXPERIMENTAL GERONTOLOGY. 44(10):666-675 (2009)</dc:description>
          <dc:description>journal article</dc:description>
          <dc:publisher>PERGAMON-ELSEVIER SCIENCE LTD</dc:publisher>
          <dc:date>2009-10</dc:date>
          <dc:format>application/pdf</dc:format>
          <dc:identifier>EXPERIMENTAL GERONTOLOGY</dc:identifier>
          <dc:identifier>10</dc:identifier>
          <dc:identifier>44</dc:identifier>
          <dc:identifier>666</dc:identifier>
          <dc:identifier>675</dc:identifier>
          <dc:identifier>0531-5565</dc:identifier>
          <dc:identifier>AA11054368</dc:identifier>
          <dc:identifier>https://soar-ir.repo.nii.ac.jp/record/3914/files/Effects_mild_calorie_restriction_high-intensity.pdf</dc:identifier>
          <dc:identifier>http://hdl.handle.net/10091/10790</dc:identifier>
          <dc:identifier>https://soar-ir.repo.nii.ac.jp/records/3914</dc:identifier>
          <dc:language>eng</dc:language>
          <dc:relation>19638306</dc:relation>
          <dc:relation>https://pubmed.ncbi.nlm.nih.gov/19638306</dc:relation>
          <dc:relation>10.1016/j.exger.2009.07.007</dc:relation>
          <dc:relation>https://doi.org/10.1016/j.exger.2009.07.007</dc:relation>
          <dc:rights>Copyright (c) 2009 Elsevier B.V.</dc:rights>
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