2024-03-29T14:52:45Z
https://soar-ir.repo.nii.ac.jp/oai
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2022-12-14T03:49:09Z
461:462
Role of Splice Variants of Gtf2i, a Transcription Factor Localizing at Postsynaptic Sites, and Its Relation to Neuropsychiatric Diseases
Shirai, Yoshinori
Li, Weidong
Suzuki, Tatsuo
postsynaptic density
synapse
local protein synthesis
transcription factor
neuropsychiatric disorders
5UTR
alternative splicing
synaptic plasticity
We previously reported that various mRNAs were associated with postsynaptic density (PSD) purified from rat forebrain. Among the thousands of PSD-associated mRNAs, we highlight the biology of the general transcription factor II-I (Gtf2i) mRNA, focusing on the significance of its versatile splicing for targeting its own mRNA into dendrites, regulation of translation, and the effects of Gtf2i expression level as well as its relationship with neuropsychiatric disorders.
Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.18(2):411(2017)
journal article
MDPI AG
2017-02-15
application/pdf
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2
18
411
1422-0067
AA12038549
https://soar-ir.repo.nii.ac.jp/record/20840/files/15K06771_01.pdf
eng
28212274
https://www.ncbi.nlm.nih.gov/pubmed/28212274
10.3390/ijms18020411
https://doi.org/10.3390/ijms18020411
© 2017 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).