@article{oai:soar-ir.repo.nii.ac.jp:00010231,
 author = {Nakamura,  Kozo and Nakajima,  Takero and Aoyama,  Toshifumi and Okitsu,  Sho and Koyama,  Masahiro},
 issue = {43},
 journal = {TETRAHEDRON},
 month = {Oct},
 note = {We developed a new one-pot reaction of phenolic acids to afford the corresponding esters and amides through acyl-protected and activated phenolic acid intermediates. The simultaneous protection/activation of phenolic acids with alkylchloroformates proceeded readily in the presence of DMAP at room temperature; subsequent addition of alcohols or amines afforded the corresponding esters or amides. The use of iso-butyloxycarbonyl as the protecting and activating group in the one-pot reactions afforded phenolic esters or amides in 91% average yield. As a practical example of this convenient synthesis, caffeic acid phenethyl ester (CAPE) was readily synthesized from commercially available caffeic acid and phenethyl alcohol in 95% yield, and an isotopomer of CAPE, [3,10-13C2]CAPE, was synthesized in 91% yield from [3-13C]caffeic acid and 2-[1-13C]phenethyl alcohol. This method may be useful for the convenient esterification and amidation of diverse phenolic acids., Article, TETRAHEDRON. 70(43):8097-8107 (2014)},
 pages = {8097--8107},
 title = {One-pot esterification and amidation of phenolic acids},
 volume = {70},
 year = {2014}
}