{"created":"2021-03-01T06:13:06.917237+00:00","id":10237,"links":{},"metadata":{"_buckets":{"deposit":"51ec5107-131c-4594-a388-ede90f755147"},"_deposit":{"id":"10237","owners":[],"pid":{"revision_id":0,"type":"depid","value":"10237"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00010237","sets":["1016:1017"]},"author_link":["32308","32309","32310"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"522","bibliographicPageStart":"510","bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"FOOD AND AGRICULTURAL IMMUNOLOGY"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The present study showed that a hot water extract of the fruiting body of the edible mushroom Boletopsis leucomelas, known as 'Kurokawa' Japanese, strongly stimulated IgA-production in mouse spleen cells in our screening experiment. The in vivo study was also conducted with the objective of enhancing adaptive immune response by oral administration of the hot water extract of B. leucomelas (BLE) in lipopolysaccharide (LPS)-challenged mice. The mice were fed a standard diet with or without 0.16% BLE. The mice were also orally administered sodium phosphate buffer or LPS weekly at days 7, 14 and 21. Results indicated that LPS-specific serum IgG, IgM and IgA were increased in the BLE diet group compared to the standard diet group. Interestingly, intestinal total IgA and LPS-specific IgA were significantly increased in the BLE diet group. Moreover, the <1000 Da, 5000-10,000 Da phenol sulphate-positive molecules from BLE showed significant IgA-producing activity.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"FOOD AND AGRICULTURAL IMMUNOLOGY. 25(4):510-522 (2014)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Shimosato, Takeshi","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.ONLCjFkV.html"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000342291100007"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"TAYLOR & FRANCIS LTD"}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1080/09540105.2013.847064"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1080/09540105.2013.847064","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is an Accepted Manuscript of an article published by Taylor & Francis in Food and Agricultural Immunology. Published online: 17 Oct 2013, available online at: http://www.tandfonline.com/10.1080/09540105.2013.847064 ."}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0954-0105","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10779820","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimosato,  Takeshi","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kanoh,  Junko","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Otani,  Hajime","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"Oral_administration_fruiting_body_extract.pdf","filesize":[{"value":"715.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Oral_administration_fruiting_body_extract.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/10237/files/Oral_administration_fruiting_body_extract.pdf"},"version_id":"d6025811-13d5-47e5-9745-9b8efd151aee"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Boletopsis leucomelas","subitem_subject_scheme":"Other"},{"subitem_subject":"Kurokawa","subitem_subject_scheme":"Other"},{"subitem_subject":"LPS challenge","subitem_subject_scheme":"Other"},{"subitem_subject":"IgA","subitem_subject_scheme":"Other"},{"subitem_subject":"adaptive immunity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Oral administration of a fruiting body extract of Boletopsis leucomelas enhances intestinal IgA production in LPS-challenged mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Oral administration of a fruiting body extract of Boletopsis leucomelas enhances intestinal IgA production in LPS-challenged mice","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["1017"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-02-12"},"publish_date":"2015-02-12","publish_status":"0","recid":"10237","relation_version_is_last":true,"title":["Oral administration of a fruiting body extract of Boletopsis leucomelas enhances intestinal IgA production in LPS-challenged mice"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:10:38.250767+00:00"}