@article{oai:soar-ir.repo.nii.ac.jp:00010248, author = {Fujii, Wataru and Toda, Kazuya and Matsumoto, Kiriko and Kawaguchi, Koichiro and Kawahara, Sei-ichi and Hattori, Yasunao and Fujii, Hiroshi and Makabe, Hidefumi}, issue = {52}, journal = {TETRAHEDRON LETTERS}, month = {Dec}, note = {Total synthesis of prodelphinidin B1, B2, and B4 has been accomplished. The key step is Lewis acid-mediated equimolar condensations between an epigallocatechin and/or a gallocatechin nucleophile and an epigallocatechin and/or a gallocatechin electrophile. The antitumor effects of synthetic prodelphinidin B1-B4 against human PC-3 prostate cancer cell lines have been investigated. These compounds showed significant antitumor effects. Their activity seemed to be little bit stronger than EGCG and prodelphinidin B3, known antitumor agent., Article, TETRAHEDRON LETTERS. 54(52):7188-7192 (2013)}, pages = {7188--7192}, title = {Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines}, volume = {54}, year = {2013} }