@article{oai:soar-ir.repo.nii.ac.jp:00010252, author = {Fujii, Wataru and Toda, Kazuya and Kawaguchi, Koichiro and Kawahara, Sei-ichi and Katoh, Miyuki and Hattori, Yasunao and Fujii, Hiroshi and Makabe, Hidefumi}, issue = {17}, journal = {TETRAHEDRON}, month = {Apr}, note = {Total synthesis of prodelphinidin B3 and C2 have been accomplished. The key step is Lewis acid-mediated equimolar condensations between a catechin and/or gallocatechin nucleophile and a gallocatechin electrophile. The antitumor effects of synthetic prodelphidin B3 and C2 against PC-3 prostate cancer cell lines have been investigated. Both compounds showed significant antitumor effects. Their activity was almost the same as that of EGCG, a known antitumor agent., Article, TETRAHEDRON. 69(17):3543-3550 (2013)}, pages = {3543--3550}, title = {Syntheses of prodelphinidin B3 and C2, and their antitumor activities through cell cycle arrest and caspase-3 activation}, volume = {69}, year = {2013} }