{"created":"2021-03-01T06:13:11.213349+00:00","id":10308,"links":{},"metadata":{"_buckets":{"deposit":"04edccd1-2d0e-4c46-9b3b-75282a8f7a83"},"_deposit":{"id":"10308","owners":[],"pid":{"revision_id":0,"type":"depid","value":"10308"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00010308","sets":["1016:1017"]},"author_link":["32621","32622","32623"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"445","bibliographicPageStart":"441","bibliographicVolumeNumber":"56","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We investigated the effect of Lactobacillus crispatus KT-11 (KT-11) on intestinal immune systems in C3H/HeN mice. The level of intestinal total immunoglobulin (Ig) A was significantly higher in mice given KT-11 than in mice not given KT-11. Gene expression relating to antibody production and innate immune response increased more than 2-fold in the former compared with the later. Moreover, the number of IL-6(+)C11b(+) cells was significantly higher in Peyer's patch cells cultured with KT-11 than in those cultured without KT-11, although the number of CD4(+) cells and the cell ratio of CD4(+)/CD8(+) were remarkably lower in the culture with KT-11. These results indicate that KT-11 enhances intestinal IgA production and innate immune response in C3H/HeN mice.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY. 56(6): 441-445(2010)","subitem_description_type":"Other"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"CENTER ACADEMIC PUBL JAPAN"}]},"item_6_relation_46":{"attribute_name":"他の資源との関係：URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.3177/jnsv.56.441"}]}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.3177/jnsv.56.441"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.3177/jnsv.56.441","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2011 by the Center for Academic Publications Japan"},{"subitem_rights":"日本ビタミン学会, 日本栄養・食糧学会"}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0301-4800","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00703822","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tobita,  Keisuke"}],"nameIdentifiers":[{"nameIdentifier":"32621","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yanaka,  Hiroyuki"}],"nameIdentifiers":[{"nameIdentifier":"32622","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Otani,  Hajime"}],"nameIdentifiers":[{"nameIdentifier":"32623","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"Lactobacillus_crispatus_KT-11_Enhances.pdf","filesize":[{"value":"118.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Lactobacillus_crispatus_KT-11_Enhances.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/10308/files/Lactobacillus_crispatus_KT-11_Enhances.pdf"},"version_id":"00a41aea-2899-4256-8f30-f308e34a1eb4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Lactobacillus crispatus KT-11","subitem_subject_scheme":"Other"},{"subitem_subject":"immunoglobulin A","subitem_subject_scheme":"Other"},{"subitem_subject":"innate immune system","subitem_subject_scheme":"Other"},{"subitem_subject":"C3H/HeN mouse","subitem_subject_scheme":"Other"},{"subitem_subject":"Peyer's patch","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["1017"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-06-20"},"publish_date":"2011-06-20","publish_status":"0","recid":"10308","relation_version_is_last":true,"title":["Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:01:59.564802+00:00"}