{"created":"2021-03-01T06:13:11.757292+00:00","id":10317,"links":{},"metadata":{"_buckets":{"deposit":"fba5f1a5-facf-4a9f-b241-50512bb078f9"},"_deposit":{"id":"10317","owners":[],"pid":{"revision_id":0,"type":"depid","value":"10317"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00010317","sets":["1016:1017"]},"author_link":["32664","32665","32666"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"705","bibliographicPageStart":"699","bibliographicVolumeNumber":"81","bibliographic_titles":[{"bibliographic_title":"ANIMAL SCIENCE JOURNAL"}]}]},"item_6_description_19":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"The definitive version is available at www.blackwell-synergy.com","subitem_description_type":"Other"}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In this study, we investigated the effects of oral ingestion of Lactobacillus crispatus KT-11 strain (KT-11) on the immune response in an allergic rhinitis mouse model, ovalbumin (OVA)-sensitized BALB/c mice. Sneezing activity in mice that were administered a KT-11-supplemented diet was significantly lower than that in mice administered a KT-11-free diet (control diet) at age 11 weeks. We found that serum OVA-specific immunoglobulin E (IgE) levels and total number of interleukin (IL)-4+CD4+ spleen cells in mice that were administered a KT-11-supplemented diet were significantly lower than in mice administered a control diet. The ratio of spleen interferon-gamma+CD4+/IL-4+CD4+ cells was higher in the mice administered the KT-11-supplemented diet compared to that in mice administered the control or L. rhamnosus GG-supplemented diet. In contrast, the number of CD11b+CD80+ and Fc epsilon RI alpha+CD117+ cells was significantly lower in mice administered the KT-11-supplemented diet. These results suggested that KT-11 reduced OVA-induced allergic symptoms in BALB/c mice via the adjustment of the T helper type 1/T helper type 2 balance, and a decrease in the number of antigen-presenting cells and high affinity IgE receptor-positive mast cells.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"ANIMAL SCIENCE JOURNAL. 81(6):699-705 (2010)","subitem_description_type":"Other"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000284643800012"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Blackwell Publishing"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"21108691"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubmed.ncbi.nlm.nih.gov/21108691/","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1111/j.1740-0929.2010.00795.x"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/j.1740-0929.2010.00795.x","subitem_relation_type_select":"DOI"}}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1344-3941","subitem_source_identifier_type":"ISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11677214","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tobita,  Keisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yanaka,  Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Otani,  Hajime"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"Anti-allergic_effects_Lactobacillus_crispatus.pdf","filesize":[{"value":"306.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Anti-allergic_effects_Lactobacillus_crispatus.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/10317/files/Anti-allergic_effects_Lactobacillus_crispatus.pdf"},"version_id":"35383795-7b72-44ef-a89b-3118c04f385c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"anti-allergic effect","subitem_subject_scheme":"Other"},{"subitem_subject":"antigen-presenting cells","subitem_subject_scheme":"Other"},{"subitem_subject":"Lactobacillus crispatus KT-11","subitem_subject_scheme":"Other"},{"subitem_subject":"mast cells","subitem_subject_scheme":"Other"},{"subitem_subject":"Th1","subitem_subject_scheme":"Other"},{"subitem_subject":"Th2 balance","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sensitized BALB/c mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sensitized BALB/c mice","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["1017"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-06-20"},"publish_date":"2011-06-20","publish_status":"0","recid":"10317","relation_version_is_last":true,"title":["Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sensitized BALB/c mice"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:30:22.508528+00:00"}