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  1. 070 農学部, 大学院農学研究科
  2. 0702 紀要 ・刊行物
  3. 07021 信州大学農学部紀要
  4. Vol. 48

特異的シナプス形成の分子メカニズム

http://hdl.handle.net/10091/15723
f2f6a491-055c-4c53-bce5-bfb0fdf047df
名前 / ファイル ライセンス アクション
Agriculture48-01.pdf Agriculture48-01.pdf (2.4 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-04-17
タイトル
タイトル 特異的シナプス形成の分子メカニズム
言語
言語 jpn
キーワード
主題Scheme Other
主題 シナプス形成
キーワード
主題Scheme Other
主題 neuronal connectivity
キーワード
主題Scheme Other
主題 ショウジョウバエ
キーワード
主題Scheme Other
主題 Drosophila
キーワード
主題Scheme Other
主題 視覚中枢
キーワード
主題Scheme Other
主題 visual system
キーワード
主題Scheme Other
主題 Nカドヘリン
キーワード
主題Scheme Other
主題 N-cadherin
キーワード
主題Scheme Other
主題 遺伝学
キーワード
主題Scheme Other
主題 genetics
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他(別言語等)のタイトル
その他のタイトル Molecular Mechanism of Neuronal Connectivity
著者 米倉, 真一

× 米倉, 真一

WEKO 33116

米倉, 真一

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信州大学研究者総覧へのリンク
氏名 米倉, 真一
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.gakFPUkh.html
出版者
出版者 信州大学農学部
引用
内容記述タイプ Other
内容記述 信州大学農学部紀要 48(1-2): 1-7(2012)
書誌情報 信州大学農学部紀要

巻 48, 号 1-2, p. 1-7, 発行日 2012-03-27
抄録
内容記述タイプ Abstract
内容記述 動物が環境刺激に適切に応答するためには,複雑であるが整然とした神経回路網の存在が必要不可欠である。この神経回路網の形成は,発生過程において,正しい相手と結合することにより形成されるが,その仕組みは分かっておらず,神経科学の学問上でも大きな謎となっている。ショウジョウバエの視覚系は,遺伝学的手法が豊富であり,シナプスの結合に特異性のあることもよく知られていることから,神経回路形成の分子機構解明に際し広く活用されている。近年,ショウジョウバエの行動解析を用いた大規模スクリーニングより,神経回路形成に関与する分子が同定されてきている。本総説では,特異的シナプス形成の分子メカニズムに関する最新の知見について述べると共に,特に,著者が明らかにした特異的シナプス形成におけるNカドヘリンの機能について紹介する。
抄録
内容記述タイプ Abstract
内容記述 An animal relies on the complex and stereotyped interneuronal connections in its brain to properlys respond to environmental stimuli. Neurons form exquisitely precise patterns of synaptic connections. Hows this is achieved during development remains a central issue in neurobiology. The Drosophila visual systems has been widely used to study the molecular mechanism of neuronal connectivity due to the powerfuls genetic tools that are available in this system. Using visual behavioral screens in Drosophila, recent studiess have identified some of the gene regulatory and cytoskeletal signaling pathways responsible for the layers -specific targeting of Drosophila photoreceptor axons. In this review, I discuss recent progress towardss understanding the molecular mechanisms that control the projection of photoreceptor axons to theirs appropriate target layers in the optic lobe. Especially, I introduce our studies about N-cadherin functionss in the neuronal connectivity.
資源タイプ(コンテンツの種類)
内容記述タイプ Other
内容記述 Article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0583-0621
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00121352
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