@article{oai:soar-ir.repo.nii.ac.jp:00010605,
 author = {Kawakami,  A and Kayahara,  H and Ajiro,  H and Tadasa,  K},
 issue = {1},
 journal = {信州大学農学部紀要},
 month = {Aug},
 note = {Inhibitory activity of glucosamine derivatives against angiotensin I converting enzyme (ACE) was investigated. Many N-substituted glucosamine derivatives were synthesized via 1,3,4,6-tetra-O-acetyl-glucosamine hydrochloride. Among them, N-(phenylalanyl-alanyl-prolyl)-glucosamine was found to be the most effective for ACE inhibition, and the half inhibitory concentrations (IC50_) was estimated as 300μM. Furthermore, N-(3,7-dimethyl-2(E/Z), 6-hexadien-carbonyl)-glucosamine and N-(p-dimethylamino benzoyl)-glucosamine were found to be effective for the inhibition of ACE, and their IC50 values were estimated as 5 mM and 8 mM, respectively., Article, 信州大学農学部紀要. 31(1): 45-54 (1994)},
 pages = {45--54},
 title = {Synthesis of N-Substituted Glucosamine Derivatives and Their Angiotensin I Converting Enzyme Inhibitory Activity},
 volume = {31},
 year = {1994}
}