{"created":"2021-03-01T06:13:32.122237+00:00","id":10652,"links":{},"metadata":{"_buckets":{"deposit":"d036b880-3c4f-42df-8709-0ef72876d00c"},"_deposit":{"id":"10652","owners":[],"pid":{"revision_id":0,"type":"depid","value":"10652"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00010652","sets":["1016:1018:1019:1043"]},"author_link":["33641","33642","33643","33644","33645","33646","33647"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"154","bibliographicPageStart":"141","bibliographicVolumeNumber":"28","bibliographic_titles":[{"bibliographic_title":"信州大学農学部紀要"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Cu-serineおよびCu-salicylate，ならびにそれらの合成に用いたCu(OH)2およびCu(NO3)2をそれぞれ50mg/kg，１群６匹の成熟雌ラットに７日間連日皮下投与し，その毒性を検討した。1)　Cu-serine群の１匹，Cu(NO3)2群の４匹が死亡した。2)　Cu-serine群の２匹で後址をつっぱって腰部をもちあげる，いわゆるロードシス反射を示唆する行動が観察された。3)　Cu-serine群およびCu(NO3)2群において著明な体重減少が認められた。4)　すべての銅化合物群で溶血性貧血が認められた。5)　肝細胞および腎尿細管上皮の変性・壊死がCu-serine群およびCu(NO3)2群で，クッパー星細胞腫大がすべての銅化合物で認められた。6)　Cu-serine群およびCu(NO3)2群で胸腺のリンパ球減少が特に著しかった。7)　これらの毒性効果は，明らかに銅そのものに起因しており，Cu-salicylateおよびCu(OH)2よりもCu-serineおよびCu(NO3)2において強かった。","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"信州大学農学部紀要. 28(2): 141-154 (1991)","subitem_description_type":"Other"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"信州大学農学部"}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0583-0621","subitem_source_identifier_type":"ISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00121352","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"茅原,  紘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"只左,  弘治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山本,  正敏"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"柴野,  隆司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"内山,  孝一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"池辺,  裕行"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中川,  博司"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"v28n02_05.pdf","filesize":[{"value":"1.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v28n02_05.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/10652/files/v28n02_05.pdf"},"version_id":"b10886a7-5bb4-47f0-9b3a-7f48a27b9683"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Copper complex","subitem_subject_scheme":"Other"},{"subitem_subject":"toxicity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"銅錯体の毒性研究（第１報） : 銅セリンと銅サリチル酸","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"銅錯体の毒性研究（第１報） : 銅セリンと銅サリチル酸","subitem_title_language":"ja"},{"subitem_title":"Toxicology of Copper Complex (Part I) Copper Serinate and Copper Salicylate","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["1043"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-12-27"},"publish_date":"2007-12-27","publish_status":"0","recid":"10652","relation_version_is_last":true,"title":["銅錯体の毒性研究（第１報） : 銅セリンと銅サリチル酸"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-05T06:42:57.867186+00:00"}