@article{oai:soar-ir.repo.nii.ac.jp:00010667,
 author = {TADASA,  Kohji and YAMAMOTO,  Yoshihiro and SHIMODA,  Ichizo and KAYAHARA,  Hiroshi},
 issue = {1・2},
 journal = {信州大学農学部紀要},
 month = {Jan},
 note = {Sonication was demonstrated to be a useful method mixing reactoin medium. A model reaction, Boc-Gly-OH + H-Phe-N₂H₂Ph → Boc-Gly-phe-N₂H₂Ph, was adopted to compare two mixing methods of medium, sonication and magnetic-stirring. Under biphasic system including 25% of organic solvent, sonication was preferable to magnetic-stirring for several cosolvents and showed being able to have some potentiality as mixing method. On the other hand another model reaction, Boc-Tyr (Bzl)-OH + H-Gly-N₂H₂Ph→Boc-Tyr (Bzl)-Gly-N₂H₂Ph, which had not been achieved by other investigators, was progressed by the new mixing method. This new method may form other certain reaction-field in the medium., Article, 信州大学農学部紀要 26(1・2): 21-26(1990)},
 pages = {21--26},
 title = {The Influence of Mixing Conditions of Reaction Medium on Protease-Catalyzed Peptide Synthesis: The Use of Sonication},
 volume = {26},
 year = {1990}
}