{"created":"2021-03-01T06:13:34.480644+00:00","id":10691,"links":{},"metadata":{"_buckets":{"deposit":"776dbff4-c70d-402f-a5be-9195814d3958"},"_deposit":{"id":"10691","owners":[],"pid":{"revision_id":0,"type":"depid","value":"10691"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00010691","sets":["1016:1018:1019:1047"]},"author_link":["33723","33724","33725"],"item_10_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"スタチン類縁体合成の中間体Buty1 1-P-Menthene-3-Azido-a-Hydroxy-7-Carboxylateの合成"}]},"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1988-01-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"146","bibliographicPageStart":"141","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"信州大学農学部紀要"}]}]},"item_10_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Protease inhibitor, pepstatin is a pentapeptide which involves two unusual amino acid, statine (3S-hydroxy-4S-amino-6-methylheptanoic acid (I)). Pepstatin is known to inhibit renin in the hypertensive renin-angiotensin system and shown to suppress blood pressure strongly. The present paper deals with the simple and convenient synthesis of butyl 1-p-menthen-3-azido-4-hydroxy-7-carboxy late (III) in which III is one of the important intermediate leading to the isosteric isomer of statin, namely, p-menthan-3-amino-2-hydroxy-7-carboxylic acid (II). Further, the acid-catalysed isomerization is also discussed.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_10_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"信州大学農学部紀要 24(2): 141-146(1988)","subitem_description_type":"Other"}]},"item_10_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"信州大学農学部"}]},"item_10_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0583-0621","subitem_source_identifier_type":"ISSN"}]},"item_10_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00121352","subitem_source_identifier_type":"NCID"}]},"item_1627890569677":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"SHIBATA,  Hisao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HASEGAWA,  Taizo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAYAHARA,  Hiroshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-25"}],"displaytype":"detail","filename":"Agriculture24-02-05.pdf","filesize":[{"value":"248.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Agriculture24-02-05.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/10691/files/Agriculture24-02-05.pdf"},"version_id":"dd018cd3-7200-48fc-aec3-e0622d998149"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Synthesis of Butyl 1-p-Menthene-3-A.zido-4-Hydroxy-7-Carboxylate, the Synthetic Intermediate of Statine Analogue","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Synthesis of Butyl 1-p-Menthene-3-A.zido-4-Hydroxy-7-Carboxylate, the Synthetic Intermediate of Statine Analogue","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["1047"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-03"},"publish_date":"2009-03-03","publish_status":"0","recid":"10691","relation_version_is_last":true,"title":["Synthesis of Butyl 1-p-Menthene-3-A.zido-4-Hydroxy-7-Carboxylate, the Synthetic Intermediate of Statine Analogue"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-05T06:46:33.744590+00:00"}