@article{oai:soar-ir.repo.nii.ac.jp:00010759, author = {TSUJII, Hirotada and MURAKAMI, Yoshinori and YOSHIDA, Motokazu}, issue = {2}, journal = {信州大学農学部紀要}, month = {Dec}, note = {Effects of progesterone and estradiol-17β on the growth and the differentiation of the mouse blastocyst during the pre-implantation and implantation stages was investigated inducing to delayed implantation by ovariectomy. When the ovariectomy was followed by daily injection of 1 mg progesterone (Group II), the area of blastocyst on the 6th day of pregnancy was significantly larger than that on the 4th day of pregnancy. When a single dose of estradiol-17β (0.5μg) was injected to ovariectomized and progesterone treated mice on the 4th or 6th day of pregnancy (Group III-A and III-B), the implantation was observed between 24 and 30 hrs. after the injection. In addition the area of blastocyst in Group III-A was significantly larger than that in Group II after 24 hrs. estradiol-17β injection and was as large as those in intact group (Group I) and Group II after 6 hrs. estradiol-1719 injection. The area of blastocyst in Group III-B was also significantly larger than that in Group II on and after 18 hrs. estradiol-17β injection. These results indicate that progesterone and estradiol-17β are important for the growth and the differentiation of delayed-implanting mouse blastocyst and they induce the implantation., Article, 信州大学農学部紀要 18(2): 133-144(1981)}, pages = {133--144}, title = {Effects of Ovarian Hormones on the Growth and the Differentiation of the Mouse Blastocyst During Delayed Implantation}, volume = {18}, year = {1981} }