{"_buckets": {"deposit": "eba6cdbf-010b-418a-b2f0-c058439755e9"}, "_deposit": {"id": "12692", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "12692"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00012692", "sets": ["1222"]}, "author_link": ["38969", "38970", "38971", "38972"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-04-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "240", "bibliographicPageStart": "235", "bibliographicVolumeNumber": "55", "bibliographic_titles": [{"bibliographic_title": "COLLOIDS AND SURFACES B-BIOINTERFACES"}]}]}, "item_6_description_30": {"attribute_name": "資源タイプ（コンテンツの種類）", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "フォーマット：mimeタイプ", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "COLLOIDS AND SURFACES B-BIOINTERFACES. 55(2): 235-240 (2007)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Okumura, Y", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.gNDVgpAF.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000245158000016"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "ELSEVIER SCIENCE BV"}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.colsurfb.2006.12.010"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.colsurfb.2006.12.010", "subitem_relation_type_select": "DOI"}}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0927-7765", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0927-7765", "subitem_source_identifier_type": "ISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10919023", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_69": {"attribute_name": "wosonly authkey", "attribute_value_mlt": [{"subitem_text_value": "liposome immobilization; cross-linked polymer gel; hydrophobic anchor; batch mode interaction; lipid adsorption"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "PHOSPHOLIPID-VESICLES; PHASE; DERIVATIVES; BEADS"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Immobilization of liposomal phospholipids onto Sephacryl S-1000 gels that were chemically conjugated with hydrophobic alkyl moieties, octyl, dodecyl and hexadecyl, was examined in batch mode interaction. Compared with the octyl gel, the dodecyl and the hexadecyl gels were found to immobilize the three to four times more phospholipids with the less hydrophobic moieties. The encapsulation of a water-soluble marker, with other evidences, suggests that the majority of the immobilized phospholipids maintained liposomal morphology. As the lipid of the interacting liposomes, egg yolk phosphatidylcholine (eggPQ, 1,2-dimyristoylphosphatidylcholine (DMPC) and a mixture of DMPC and 1,2-dimyristamido-2-deoxyphosphatidylcholine were examined. At 22 degrees C, DMPC liposomes showed higher extent of immobilization than at 37 degrees C but not eggPC liposomes, suggesting that the phase of liposomal membrane could have influence on the immobilization. Exchange between the immobilized liposomes and free ones was found to be small, less than 3%. The gel that had been first interacted with liposomes to apparent saturation could further immobilize the newly added liposomes. The rate of this second immobilization was similar to that of the slow adsorption process; the both could be based on the same mechanism, possibly involving rearrangement of the immobilized liposomes on the gel as proposed by Lundahl. As had been observed in the flow mode, the immobilization had preference for smaller liposomes. In application of the system in batch mode, the size distributions of the immobilized liposomes and of those left in the Supernatant may differ from that of the originally added liposomes. (C) 2007 Elsevier B.V. All rights reserved."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Okumura,  Y"}], "nameIdentifiers": [{"nameIdentifier": "38969", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizushima,  H"}], "nameIdentifiers": [{"nameIdentifier": "38970", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fujinaga,  K"}], "nameIdentifiers": [{"nameIdentifier": "38971", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sunamoto,  J"}], "nameIdentifiers": [{"nameIdentifier": "38972", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "csbb.pdf", "filesize": [{"value": "256.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 256100.00000000003, "url": {"label": "csbb.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/12692/files/csbb.pdf"}, "version_id": "47bbfc8b-cfb0-4c6c-831a-0e411e9ad9cf"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Immobilization of liposomes on hydrophobically modified polymer gel particles in batch mode interaction", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Immobilization of liposomes on hydrophobically modified polymer gel particles in batch mode interaction", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["1222"], "permalink_uri": "http://hdl.handle.net/10091/402", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-10-30"}, "publish_date": "2007-10-30", "publish_status": "0", "recid": "12692", "relation": {}, "relation_version_is_last": true, "title": ["Immobilization of liposomes on hydrophobically modified polymer gel particles in batch mode interaction"], "weko_shared_id": -1}