{"created":"2021-03-01T06:16:13.639026+00:00","id":13302,"links":{},"metadata":{"_buckets":{"deposit":"bf4390a3-5ca3-419a-95d6-81035dcbc6d6"},"_deposit":{"id":"13302","owners":[],"pid":{"revision_id":0,"type":"depid","value":"13302"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00013302","sets":["1309:1310"]},"author_link":["40285","40286","40287","40288","40289","40290","40291","40292"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"365","bibliographicPageStart":"360","bibliographicVolumeNumber":"115","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF BIOSCIENCE AND BIOENGINEERING"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A full-length cDNA coding for a putative adenosine deaminase (Fv-ada) was isolated from the basidiomycete Flammulina velutipes. Fv-ada encodes a polypeptide consisting of 537 amino acid residues, which has a consensus sequence conserved among adenosine deaminase-related growth factors (ADGF) found in several metazoa, including chordates and insects. Fv-ada transcript was detected at all stages of growth in dikaryotic F. velutipes cells, with a peak at the primordial stage. Heterologous expression of Fv-ada in the yeast Pichia pastoris produced recombinant Fv-ADA that catalyzed the conversion of adenosine to inosine. Dikaryotic mycelia from F. velutipes were transformed with the binary plasmid pFungiway-Fv-ada, which was designed to suppress the expression of Fv-ada through RNA interference. The growth rates of the resulting transformants were retarded in response to the degree of suppression, indicating that Fv-ada plays an important role in the mycelial growth of F. velutipes. These results suggested that ADGF could function as growth factors in fungi, as is seen in other eukaryotes.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"JOURNAL OF BIOSCIENCE AND BIOENGINEERING. 115(4):360-365 (2013)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Taguchi, Goro","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.uCDpjekV.html"},{"subitem_link_text":"Shimosaka, Makoto","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.ZekmjekV.html"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000318383400003"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"SOC BIOSCIENCE BIOENGINEERING JAPAN"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"23177216"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=23177216","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1016/j.jbiosc.2012.10.020"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.jbiosc.2012.10.020","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright© 2012 The Society for Biotechnology, Japan."}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1389-1723","subitem_source_identifier_type":"ISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11307678","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sekiya,  Shuichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada,  Masato"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shibata,  Kou"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okuhara,  Toru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida,  Masumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Inatomi,  Satoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taguchi,  Goro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimosaka,  Makoto"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-28"}],"displaytype":"detail","filename":"Characterization_gene_coding_putative_adenosine.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Characterization_gene_coding_putative_adenosine.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/13302/files/Characterization_gene_coding_putative_adenosine.pdf"},"version_id":"601b5a40-a65d-4f9b-9551-6a65db9d75c1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Adenosine deaminase","subitem_subject_scheme":"Other"},{"subitem_subject":"Basidiomycete","subitem_subject_scheme":"Other"},{"subitem_subject":"Flammulina velutipes","subitem_subject_scheme":"Other"},{"subitem_subject":"Growth factor","subitem_subject_scheme":"Other"},{"subitem_subject":"RNA interference","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Characterization of a gene coding for a putative adenosine deaminase-related growth factor by RNA interference in the Basidiomycete Flammulina velutipes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Characterization of a gene coding for a putative adenosine deaminase-related growth factor by RNA interference in the Basidiomycete Flammulina velutipes","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["1310"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-09-05"},"publish_date":"2014-09-05","publish_status":"0","recid":"13302","relation_version_is_last":true,"title":["Characterization of a gene coding for a putative adenosine deaminase-related growth factor by RNA interference in the Basidiomycete Flammulina velutipes"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:03:27.741449+00:00"}