@techreport{oai:soar-ir.repo.nii.ac.jp:00014462, author = {中垣, 雅雄 and 八森, 章}, month = {Mar}, note = {The purpose of this study is to make silkworm which spin spider's silk. Spider silk is a materials science wonder. A self-assembling, biodegradable, high-performance, nano-fiber structure that can stop a bee traveling at full speed without breaking. Despite its unique properties, attempts to produce spider silk in large quantities by domesticating spiders have failed until now. Silkworms might be able to produce threads that compare well with spider silk by having their silk genes altered. Silkworms are worms which produce silk. Silk production by silkworms is eco-friendly. I have employed germline transformation using the piggyBac vector to breed transgenic silkworms that produce cocoons containing recombinant spider silk. There are several kinds of spider silk. I transposed a flagelliform silk gene to genome DNA of a silkworm. It was confirmed that the flagelliform silk protein was included in a cocoon which was made by the trasgenic silkworm. The content of flagelliform silk protein in cocoon protein was one or two percent. Experiment to raise the content and experiment to transpose a dragline silk gene or a egg case silk gene to silkworm genome are now performed., Article, 先進ファイバー工学研究教育拠点研究成果報告書 11: 41-41(2005)}, title = {15-2-3 : 蚕に蜘妹の糸を吐かせる研究}, year = {2005} }