@techreport{oai:soar-ir.repo.nii.ac.jp:00014603, author = {山本, 浩之}, month = {Mar}, note = {Natural protein fibers such as silk having high-performance characteristics have been an important material in the research for biopolymers. This article reports development of a silk-like extensible poly(α, L-amino acid) fiber inspired by self-assembly of polypeptides in living systems. Electrostatic interaction was employed as the driving force for building the fiber, and succeeded in spinning the fiber from an aqueous solution interface between poly(α, L-lysine) (PLL) and poly(α, L-glutamic acid) (PLG). When the PLL/PLG fiber was formed, the conformations of PLL and PLG were changed from random- to β-structures. A remarkable feature of the PLL/PLG fiber is the high extensibility. Mechanical stretching of the PLL/PLG fiber resulted in a change from an extensible fiber to a rigid and strong fiber. These features depend on molecular conformation and the deviation in the amino acid composition of the PLL/PLG fibers. This concept and the poly α, L-amino acid) fibers themselves pioneer the production of new protein fibers and the science of protein folding as the noncovalent interactions involved in self-assembly., Article, 先進ファイバー工学研究教育拠点研究成果報告書 10: 81-81(2004)}, title = {15-3-12 :バイオミメティック繊維の創成}, year = {2004} }