{"created":"2021-03-01T06:22:08.709822+00:00","id":19070,"links":{},"metadata":{"_buckets":{"deposit":"5fad48fa-6d6f-4668-8c7d-d2bd0f0ae660"},"_deposit":{"id":"19070","owners":[],"pid":{"revision_id":0,"type":"depid","value":"19070"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00019070","sets":["461:462"]},"author_link":["104039","104040","104041","104042","104043","104044","104045","104046","104047","104048","104049","104050","104051","104052","104053"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-03-17","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"8","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"BEHAVIORAL AND BRAIN FUNCTIONS"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND: Patients with Alzheimer's disease (AD) often present with apathy symptoms resembling the decreased motivation observed in depressed patients. Therefore, differentiating the initial phase of AD from late life depression may be difficult in some cases. Near-infrared spectroscopy (NIRS) is a functional neuroimaging modality that uses near-infrared light to measure changes in hemoglobin concentration on the cortical surface during activation tasks. The objective of this study was to investigate differences in brain activation associated with late life depression and with AD by means of NIRS. METHODS: NIRS was performed in 30 patients with depression, 28 patients with AD, and 33 healthy controls, all aged 60 years or older. During two tasks, a verbal fluency task and a visuospatial task, changes in oxygenated hemoglobin concentration in the frontal and parietal cortices were investigated. RESULTS: In the visuospatial task, cortical activation was lower in the depressed group than in the AD group, and significant differences were observed in the parietal cortex. CONCLUSIONS: NIRS can detect differences in brain activation between patients with late life depression and those with AD. NIRS is a promising tool for the differential diagnosis of late life depression and AD. ","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"BEHAVIORAL AND BRAIN FUNCTIONS. 10:8 (2014)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Sasayama, Daimei","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.uNkegpkh.html"},{"subitem_link_text":"Sugiyama, Nobuhiro","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.yVAmjNSN.html"},{"subitem_link_text":"Ogihara, Tomomi","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.jhLUgpkh.html"},{"subitem_link_text":"Hagiwara, Tetsuya","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.jFLeuNkh.html"},{"subitem_link_text":"Takahashi, Tohru","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.uVnmuakh.html"},{"subitem_link_text":"Nose, Hiroshi","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.HUyVuUkh.html"},{"subitem_link_text":"Hanihara, Tokiji","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.ZCkmHVkh.html"},{"subitem_link_text":"Washizuka, Shinsuke","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.uhnNuakh.html"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BIOMED CENTRAL LTD"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"24636630"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubmed.ncbi.nlm.nih.gov/24636630","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1186/1744-9081-10-8"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1186/1744-9081-10-8","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© Kito et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated."}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1744-9081","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12050307","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kito, Hisashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104039","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ryokawa, Akiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104040","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kinoshita, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104041","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sasayama, Daimei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104042","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugiyama, Nobuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104043","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogihara, Tomomi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104044","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasaki, Takehiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104045","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hagiwara, Tetsuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104046","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inuzuka, Shin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104047","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahashi, Tohru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104048","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Genno, Hirokazu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104049","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nose, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104050","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hanihara, Tokiji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104051","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Washizuka, Shinsuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104052","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Amano, Naoji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"104053","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-20"}],"displaytype":"detail","filename":"Comparison_alterations_cerebral_hemoglobin_oxygenation.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensefree":"© Kito et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. 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