{"created":"2022-11-14T02:56:06.092376+00:00","id":2001236,"links":{},"metadata":{"_buckets":{"deposit":"4fcb6cad-8ebf-4677-a72c-9c604ee8a486"},"_deposit":{"id":"2001236","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2001236"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:02001236","sets":["461:462"]},"author_link":[],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-10-14","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"1442","bibliographicPageStart":"1433","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Microbial Drug Resistance"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of this study was to investigate the presence of colistin- and/or tigecycline-resistant Klebsiella spp. in influents from four wastewater treatment plants (WWTPs), which partly reflect the gut microbiome of human populations. Colistin- and tigecycline-resistant Klebsiella pneumoniae isolates (K30/ST29) were detected four times from the WWTP A during a period of 3 months. Disruptions of the mgrB and ramR genes by ISEc68 and ISKpn21, respectively, were identified in those four isolates. They also shared the IncL/M 86,197-bp plasmids carrying a bla(CTX-M-3) and Tn1548-associated armA [IS26-IntI1-dfrA12-gucF-aadA2-qacE Delta 1-sul1-ISCR1-ISEc28-armA-ISEc29-msr(E)-mph(E)-IS26]. Those isolates formed a distinct cluster within wgMLST clusters of ST29 K30 public reference strains of human origin and were unique due to harboring of Tn21-like mercury resistance operon transposons in addition to silver, copper, and arsenic resistance determinants. Five K. pneumoniae strains with different STs and 1 Klebsiella quasipneumoniae strain, exhibiting colistin resistance, were detected in WWTPs B, C, and D. For these isolates, disruptions of mgrB by ISEc68 (three isolates) or ISEcl1 (one isolate), insertion of IS2 in the mgrB promoter region (one isolate), and inactivation of MgrB by a nonsense mutation (one isolate) were identified. Close monitoring of these mcr-negative colistin- and/or tigecycline-resistant bacteria in wastewater influents is imperative to avoid further limiting of treatment options.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Microbial Drug Resistance 27(10) : 1433-1442(2021)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"長野, 由紀子","subitem_link_url":"https://soar-rd.shinshu-u.ac.jp/profile/ja.OUAeumyC.html"},{"subitem_link_text":"長野, 則之","subitem_link_url":"https://soar-rd.shinshu-u.ac.jp/profile/ja.HULFumkh.html"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Marry Ann"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"33835858"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubmed.ncbi.nlm.nih.gov/33835858/","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1089/mdr.2020.0514"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1089/mdr.2020.0514","subitem_relation_type_select":"DOI"}}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1931-8448","subitem_source_identifier_type":"EISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11056498","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayashi, Wataru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Iimura, Masaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Soga, Eiji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Koide, Shota","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Izumi, Katsutoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yoshida, Satoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Arakawa, Yoshichika","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagano, Yukiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagano, Noriyuki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-11-14"}],"filename":"18K08428_6.pdf","format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"18K08428_6.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/2001236/files/18K08428_6.pdf"},"version_id":"2020ac3b-de42-4e04-a0fd-5455e50332c9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"colistin","subitem_subject_scheme":"Other"},{"subitem_subject":"tigecycline","subitem_subject_scheme":"Other"},{"subitem_subject":"mgrB","subitem_subject_scheme":"Other"},{"subitem_subject":"ramR","subitem_subject_scheme":"Other"},{"subitem_subject":"K. pneumoniae","subitem_subject_scheme":"Other"},{"subitem_subject":"WWTPs","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Presence of Colistin- and Tigecycline-Resistant Klebsiella pneumoniae ST29 in Municipal Wastewater Influents in Japan","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Presence of Colistin- and Tigecycline-Resistant Klebsiella pneumoniae ST29 in Municipal Wastewater Influents in Japan","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["462"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-11-14"},"publish_date":"2022-11-14","publish_status":"0","recid":"2001236","relation_version_is_last":true,"title":["Presence of Colistin- and Tigecycline-Resistant Klebsiella pneumoniae ST29 in Municipal Wastewater Influents in Japan"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:42:42.589053+00:00"}