@article{oai:soar-ir.repo.nii.ac.jp:02001272,
 author = {Tsuchiya, Ryoma and Kaneshima, Aino and Kobayashi, Masakazu and Yamazaki, Maki and Takasu, Yoko and Sezutsu, Hideki and Tanaka, Yoshiaki and Mizoguchi, Akira and Shiomi, Kunihiro},
 issue = {1},
 journal = {Proceedings of The National Academy of Sciences of The United States of America},
 month = {Jan},
 note = {Diapause represents a major developmental switch in insects and is a seasonal adaptation that evolved as a specific subtype of dormancy in most insect species to ensure survival under unfavorable environmental conditions and synchronize populations. However, the hierarchical relationship of the molecular mechanisms involved in the perception of environmental signals to integration in morphological, physiological, behavioral, and reproductive responses remains unclear. In the bivoltine strain of the silkworm Bombyx mori, embryonic diapause is induced transgenerationally as a maternal effect. Progeny diapause is determined by the environmental temperature during embryonic development of the mother. Here, we show that the hierarchical pathway consists of a gamma-aminobutyric acid (GABA)ergic and corazonin signaling system modulating progeny diapause induction via diapause hormone release, which may be finely tuned by the temperature-dependent expression of plasma membrane GABA transporter. Furthermore, this signaling pathway possesses similar features to the gonadotropin-releasing hormone (GnRH) signaling system for seasonal reproductive plasticity in vertebrates., Article, Proceedings of The National Academy of Sciences of The United States of America 118(1) : e2020028118-(2021)},
 title = {Maternal GABAergic and GnRH/corazonin pathway modulates egg diapause phenotype of the silkworm Bombyx mori},
 volume = {118},
 year = {2021}
}