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Genetic factors affect the etiology, clinical characteristics and outcome of autoimmune hepatitis
http://hdl.handle.net/10091/00020996
http://hdl.handle.net/10091/00020996ac8eae0a-a97a-41d8-b51a-12b8082ba0ad
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-10-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Genetic factors affect the etiology, clinical characteristics and outcome of autoimmune hepatitis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HLA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Autoimmune hepatitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Primary biliary cirrhosis | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Umemura, Takeji
× Umemura, Takeji× Ota, Masao |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Umemura, Takeji | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ymSpgpkh.html | |||||
出版者 | ||||||
出版者 | Springer | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Clinical Journal of Gastroenterology.8(6):360-366(2015) | |||||
書誌情報 |
Clinical Journal of Gastroenterology 巻 8, 号 6, p. 360-366, 発行日 2015-12-10 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Autoimmune hepatitis (AIH) is characterized by chronic inflammation of the liver, hypergammaglobulinemia, the presence of serum autoantibodies, histologic evidence of interface hepatitis, and a favorable response to immunosuppressive treatment. Although the etiology of AIH remains undefined, human leukocyte antigen (HLA) class II alleles have been associated with disease onset for decades. AIH resistance and severity are presumably linked to HLA alleles as well. Individuals in different geographic regions of the world may have varying susceptibility alleles that reflect indigenous triggering antigens. In this review, we describe the influence of HLA alleles and gene polymorphisms on AIH, along with the results of genome-wide association studies on this disease. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1865-7257 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12646624 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://www.ncbi.nlm.nih.gov/pubmed/26661115 | |||||
関連名称 | 26661115 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s12328-015-0620-9 | |||||
関連名称 | 10.1007/s12328-015-0620-9 | |||||
権利 | ||||||
権利情報 | The final publication is available at link.springer.com | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |