@article{oai:soar-ir.repo.nii.ac.jp:00020804,
 author = {Osada, Mitsumasa and Kobayashi, Hisaya and Miyazawa, Tatsuya and Suenaga, Shin and Ogata, Makoto},
 journal = {INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES},
 month = {Sep},
 note = {Epub 2019 June 21, The non-catalytic conversion of chitin into N-acetyl-ᴅ-glucosamine (GlcNAc) derivatives such as 2-acetamido-2,3-dideoxy-ᴅ-erythro-hex-2-enofuranose (Chromogen I) was investigated in high-temperature water at 290–390 °C and 25 MPa with a reaction time of 0–180 min. High-temperature water treatment is a promising method for chitin conversion as it does not require the use of any additional organic solvents or ionic liquids. A semi-batch reactor was developed to control the reaction temperature and time. It was found that the chitin powder could be converted into a water-soluble fraction in ~90% yield, with Chromogen I being obtained in a maximum yield of 2.6%. Furthermore, a kinetic model was developed to estimate the reaction rate for the conversion of the chitin powder to the water-soluble fraction., Article, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 136:994-999 (2019)},
 pages = {994--999},
 title = {Non-catalytic conversion of chitin into Chromogen I in high-temperature water},
 volume = {136},
 year = {2019}
}