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Patients with CDH23 mutations and the 1555A > G mitochondrial mutation are good candidates for electric acoustic stimulation (EAS)
http://hdl.handle.net/10091/17788
http://hdl.handle.net/10091/177889485d542-71f9-45a4-b1cc-d5ad022f2e41
| 名前 / ファイル | ライセンス | アクション |
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Patients_CDH23_mutations_1555AG_mitochondrial.pdf (476.9 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2014-07-25 | |||||||||||||||||||||
| タイトル | ||||||||||||||||||||||
| タイトル | Patients with CDH23 mutations and the 1555A > G mitochondrial mutation are good candidates for electric acoustic stimulation (EAS) | |||||||||||||||||||||
| 言語 | ||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||
| DOI | ||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.3109/00016489.2011.649493 | |||||||||||||||||||||
| 関連名称 | 10.3109/00016489.2011.649493 | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 主題 | Residual hearing, hearing preservation, gene, mitochondria, 12S rRNA | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| タイプ | journal article | |||||||||||||||||||||
| 著者 |
Usami, Shin-ichi
× Usami, Shin-ichi
× Miyagawa, Maiko
× Nishio, Shin-Ya
× Moteki, Hideaki
× Takumi, Yutaka
× Suzuki, Mika
× Kitano, Yoko
× Iwasaki, Satoshi
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| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Usami, Shin-ichi | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.ZmAUHUSC.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Nishio, Shin-Ya | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.uCSmPpym.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Moteki, Hideaki | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HNcauNkh.html | |||||||||||||||||||||
| 信州大学研究者総覧へのリンク | ||||||||||||||||||||||
| 氏名 | Takumi, Yutaka | |||||||||||||||||||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HNnNHhSC.html | |||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||
| 出版者 | INFORMA HEALTHCARE | |||||||||||||||||||||
| 引用 | ||||||||||||||||||||||
| 内容記述 | ACTA OTO-LARYNGOLOGICA. 132(4):377-384 (2012) | |||||||||||||||||||||
| 書誌情報 |
ACTA OTO-LARYNGOLOGICA 巻 132, 号 4, p. 377-384, 発行日 2012-04 |
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| 抄録 | ||||||||||||||||||||||
| 内容記述 | Conclusions: CDH23 mutations and the 1555A>G mitochondrial mutation were identified among our series of electric acoustic stimulation (EAS) patients, confirming that these genes were important in hearing loss with involvement of high frequency. Successful hearing preservation as well as good outcomes from EAS indicated that patients with this combination of mutations are good candidates for EAS. Objectives: Screening for gene mutations that possibly cause hearing loss involving high frequency was performed to identify the responsible genes in patients with EAS. In addition to a review of the genetic background of the patients with residual hearing loss, the benefit of EAS for patients with particular gene mutations was evaluated. Methods: Eighteen patients (15 late-onset, 3 early-onset) with residual hearing who had received EAS were included in this study. Genetic analysis was performed to identify GJB2, CDH23, SLC26A4, and the 1555 mitochondrial mutations. Results: Three early-onset patients had CDH23 mutations. One late-onset patient had the 1555 A>G mitochondrial mutation. | |||||||||||||||||||||
| 資源タイプ（コンテンツの種類） | ||||||||||||||||||||||
| ISSN | ||||||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||||||
| 収録物識別子 | 0001-6489 | |||||||||||||||||||||
| 書誌レコードID | ||||||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||||||
| 収録物識別子 | AA0050923X | |||||||||||||||||||||
| PubMed | ||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/22443853 | |||||||||||||||||||||
| 関連名称 | 22443853 | |||||||||||||||||||||
| 権利 | ||||||||||||||||||||||
| 権利情報 | Copyright© 2012 Informa Healthcare | |||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
| WoS | ||||||||||||||||||||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000302068700006 | |||||||||||||||||||||
