| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2014-07-25 |
| タイトル |
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|
タイトル |
IgG4-related chronic rhinosinusitis: A new clinical entity of nasal disease |
| 言語 |
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|
言語 |
eng |
| DOI |
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|
関連識別子 |
https://doi.org/10.3109/00016489.2010.533699 |
|
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関連名称 |
10.3109/00016489.2010.533699 |
| キーワード |
|
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主題 |
IgG4-related disease, high serum IgG4, steroids |
| 資源タイプ |
|
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資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 著者 |
Moteki, Hideaki
Yasuo, Masanori
Hamano, Hideaki
Uehara, Takeshi
Usami, Shin-ichi
|
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Moteki, Hideaki |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.HNcauNkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Yasuo, Masanori |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.ypnegpkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Uehara, Takeshi |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.jNyegpkh.html |
| 信州大学研究者総覧へのリンク |
|
|
氏名 |
Usami, Shin-ichi |
|
URL |
http://soar-rd.shinshu-u.ac.jp/profile/ja.ZmAUHUSC.html |
| 出版者 |
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出版者 |
INFORMA HEALTHCARE |
| 引用 |
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内容記述 |
ACTA OTO-LARYNGOLOGICA. 131(5):518-526 (2011) |
| 書誌情報 |
ACTA OTO-LARYNGOLOGICA
巻 131,
号 5,
p. 518-526,
発行日 2011-05
|
| 抄録 |
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内容記述 |
Conclusion: IgG4-related disease involves nasal manifestations with chronic rhinosinusitis (CRS). This type of sinusitis is a new clinical entity of nasal disease associated with a high level of serum IgG4 for which steroid therapy is effective. Objectives. To confirm whether IgG4-related disease has distinctive chronic rhinosinusitis. Methods: We compared serum IgG4 levels as well as nasal computed tomography (CT) and clinicopathological findings before and after glucocorticoid treatment in 31 patients diagnosed as having IgG4-related disease with nasal manifestations. To evaluate immunohistochemical findings of nasal mucosa, we compared them with IgG4-related CRS and common CRS. Results: All patients had levels of high serum IgG4. Ten of the 31 patients had nasal obstruction, nasal discharge, postnasal discharge, hyposmia, and dull headache. They also demonstrated sinus lesions on radiological findings. After glucocorticoid treatment, serum IgG and IgG4 levels were markedly decreased and along with improvement of the symptoms, nasal sinus CT findings also revealed improvement of the sinus opacification. In immunohistochemical examination, the magnitude of IgG4-positive plasma cell infiltration in common CRS was almost the same as in the IgG4-related CRS group. Therefore, in nasal mucosa immunocytochemical positive staining for IgG4 is not specific for definition of IgG4-related disease. |
| 資源タイプ（コンテンツの種類） |
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| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0001-6489 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0050923X |
| PubMed |
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|
識別子タイプ |
PMID |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/21162659 |
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関連名称 |
21162659 |
| 権利 |
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|
権利情報 |
Copyright© 2011 Informa Healthcare |
| 出版タイプ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| WoS |
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|
URL |
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000289562600010 |
IgG4-related_chronic_rhinosinusitis_new_clinical_entity.pdf (465.9 kB)
