@article{oai:soar-ir.repo.nii.ac.jp:00003693, author = {Sasayama, Daimei and Hori, Hiroaki and Teraishi, Toshiya and Hattori, Kotaro and Ota, Miho and Matsuo, Junko and Kawamoto, Yumiko and Kinoshita, Yukiko and Amano, Naoji and Kunugi, Hiroshi}, issue = {3}, journal = {JOURNAL OF NEURAL TRANSMISSION}, month = {Mar}, note = {Wechsler adult intelligence scale-revised was performed in 576 healthy adults to examine whether a functional polymorphism (Asp358Ala) of the IL-6 receptor (IL-6R) gene is associated with cognitive performance. Verbal intelligence quotient in Asp homozygotes was significantly higher compared to Ala carriers (P = 0.005). Compared to Ala carriers, Asp homozygotes performed better in the verbal subtests requiring long-term memory stores. Elevated IL-6 and soluble IL-6R levels in Ala carriers may have negative impact on acquiring verbal cognitive ability requiring long-term memory., Article, JOURNAL OF NEURAL TRANSMISSION. 119(3):313-318 (2012)}, pages = {313--318}, title = {Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults}, volume = {119}, year = {2012} }