@article{oai:soar-ir.repo.nii.ac.jp:00003706, author = {Yamazaki, Masanori and Sato, Ai and Nishio, Shin-ichi and Takeda, Teiji and Miyamoto, Takahide and Katai, Miyuki and Hashizume, Kiyoshi}, issue = {6}, journal = {INTERNAL MEDICINE}, month = {}, note = {A 33-year-old woman was hospitalized for examination of edematous laryngopharynx. She was acromegalic. A pituitary adenoma with elevated serum levels of growth hormone (GH) and insulin-like growth factor-I (IGF-I) was detected, indicating acromegaly caused by GH-secreting pituitary adenoma. Multiple pigmented nevi were also noted without overt short stature and cubitus valgus. Chromosome analysis revealed that she had contracted Turner syndrome with 47,XXX/45,X/46,XX mosaicism. Transsphenoidal resection of the tumor decreased serum GH and IGF-I levels, but the edema was not improved. Both premature ovarian failure and hypertension appeared after surgery. This case may indicate the important relationships between GH/IGF-I and Turner syndrome., Article, INTERNAL MEDICINE. 48(6):447-453 (2009)}, pages = {447--453}, title = {Acromegaly Accompanied by Turner Syndrome with 47,XXX/45,X/46,XX Mosaicism}, volume = {48}, year = {2009} }