@article{oai:soar-ir.repo.nii.ac.jp:00003740,
 author = {Komatsu,  Yoshimichi and Yamamoto,  Hiroshi and Tsushima,  Kenji and Furuya,  Shino and Yoshikawa,  Sumiko and Yasuo,  Masanori and Kubo,  Keishi and Yamazaki,  Yoshitaka and Hasegawa,  Joh and Eguchi,  Takashi and Kondo,  Ryuichi and Yoshida,  Kazuo and Koizumi,  Tomonobu},
 issue = {6},
 journal = {INFLAMMATION},
 month = {Dec},
 note = {The present study was designed to evaluate inflammatory changes in collapsed lungs during one-lung ventilation using the assistance of a bronchoscopic microsampling probe. Serial albumin and interleukin (IL)-8 concentrations in epithelial lining fluid (ELF) were measured in seven patients undergoing resection of lung tumors. The samples were taken after induction of anesthesia (baseline), 30 min after one-lung ventilation was started (point 2), just before resuming two-lung ventilation (point 3), and 30 min after two-lung ventilation was restarted (point 4). The albumin and IL-8 concentrations in ELF were significantly increased at point 2 and point 3, respectively, and remained to be high, compared to the baseline. The increase in IL-8 at point 3 was correlated with the interval of one-lung ventilation; however, none developed specific acute lung injury. These findings suggest that inflammatory changes can occur on the epithelium of a collapsed lung even in patients who underwent successful and standard thoracic surgery., Article, INFLAMMATION. 35(6):1844-1850 (2012)},
 pages = {1844--1850},
 title = {Increased Interleukin-8 in Epithelial Lining Fluid of Collapsed Lungs During One-Lung Ventilation for Thoracotomy},
 volume = {35},
 year = {2012}
}