{"created":"2021-03-01T06:07:37.360591+00:00","id":3789,"links":{},"metadata":{"_buckets":{"deposit":"2933f43d-fdb2-460b-add8-f8fcc262c207"},"_deposit":{"id":"3789","owners":[],"pid":{"revision_id":0,"type":"depid","value":"3789"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00003789","sets":["461:462"]},"author_link":["7049","7050","7051","7052","7053"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"111","bibliographicPageStart":"107","bibliographicVolumeNumber":"278","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF THE NEUROLOGICAL SCIENCES"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The clinical effect of the GABAergic drug gabapentin was evaluated in 11 patients with spinocerebellar ataxia type 6 (SCA6). The total period of gabapentin treatment was 4 weeks, and outcome measures were determined with the International Cooperative Ataxia Rating Scales (ICARS) and postural sway studies. At week 4, 5 patients showed a decrease of the ICARS values by more than 10% compared with the pretreatment baseline. Eight patients showed a more than 10% decrease of the sway area (SA) and/or sway path length (SPL) values in postural sway Studies. The ICARS values and SA/SPL values were not necessarily consistent in each patient, but 3 patients showed a more than 10% decrease in the ICRAS, SA, and SPL values at week 4 when compared to the pre-treatment baseline. As a whole, the efficacy of gabapentin was not statistically confirmed in the 4-week trial because of the variation in efficacy in each patient, but the data are indicative that some SCA6 patients could benefit from gabapentin treatment.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"JOURNAL OF THE NEUROLOGICAL SCIENCES. 278(1-2):107-111 (2009)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Yoshida, Kunihiro","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.yhfNHFkh.html"},{"subitem_link_text":"Morita, Hiroshi","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.HUyNHhkh.html"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000263692300021"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"ELSEVIER SCIENCE BV"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"19157422"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubmed.ncbi.nlm.nih.gov/19157422","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1016/j.jns.2008.12.017"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.jns.2008.12.017","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright© 2008 Elsevier B.V."}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-510X","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00703265","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakamura,  Katsuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida,  Kunihiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyazaki,  Daigo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morita,  Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikeda,  Shu-ichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-24"}],"displaytype":"detail","filename":"Spinocerebellar_ataxia_type_6_SCA6.pdf","filesize":[{"value":"315.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Spinocerebellar_ataxia_type_6_SCA6.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/3789/files/Spinocerebellar_ataxia_type_6_SCA6.pdf"},"version_id":"a5de6efe-2f71-4bd5-9d2a-ba43b9ef23c5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Spinocerebellar ataxia type 6 (SCA6)","subitem_subject_scheme":"Other"},{"subitem_subject":"Gabapentin","subitem_subject_scheme":"Other"},{"subitem_subject":"The International Cooperative Ataxia Rating Scales (ICARS)","subitem_subject_scheme":"Other"},{"subitem_subject":"Voltage-dependent calcium channel (VDCC)","subitem_subject_scheme":"Other"},{"subitem_subject":"gamma-aminobutyric acid (GABA)","subitem_subject_scheme":"Other"},{"subitem_subject":"Postural sway study","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["462"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-04-01"},"publish_date":"2013-04-01","publish_status":"0","recid":"3789","relation_version_is_last":true,"title":["Spinocerebellar ataxia type 6 (SCA6): Clinical pilot trial with gabapentin"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:40:17.992881+00:00"}