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Risk Factors for Severe Dysphagia after Concurrent Chemoradiotherapy for Head and Neck Cancers
http://hdl.handle.net/10091/16251
http://hdl.handle.net/10091/16251baed73ea-0007-4311-b831-469b35fa3649
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-02-13 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Risk Factors for Severe Dysphagia after Concurrent Chemoradiotherapy for Head and Neck Cancers | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | toxicity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | combined modality therapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | head and neck neoplasm | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dysphagia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | radiotherapy | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Koiwai, Keiichiro
× Koiwai, Keiichiro× Shikama, Naoto× Sasaki, Shigeru× Shinoda, Atsunori× Kadoya, Masumi |
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信州大学研究者総覧へのリンク | ||||||
氏名 | Koiwai, Keiichiro | |||||
URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gCkCgUkh.html | |||||
出版者 | ||||||
出版者 | OXFORD UNIV PRESS | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JAPANESE JOURNAL OF CLINICAL ONCOLOGY. 39(7):413-417 (2009) | |||||
書誌情報 |
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 巻 39, 号 7, p. 413-417, 発行日 2009-07 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of this study was to investigate the risk factors for dysphagia induced by chemoradiotherapy for head and neck cancers. Forty-seven patients with head and neck cancers who underwent definitive chemoradiotherapy from December 1998 to March 2006 were reviewed retrospectively. Median age was 63 years (range, 16-81). The locations of the primary lesion were as follows: larynx in 18 patients, oropharynx in 11, nasopharynx in 7, hypopharynx in 7 and others in 4. Clinical stages were as follows: Stage II in 20 and Stages III-IV in 27. Almost all patients underwent platinum-based concomitant chemoradiotherapy. The median cumulative dose of cisplatin was 100 mg/m(2) (range, 80-300) and median radiation dose was 70 Gy (range, 50-70). Severe dysphagia (Grade 3-4) was observed in 22 patients (47%) as an acute toxic event. One patient required tube feeding even at 12-month follow-up. In univariate analysis, clinical stage (III-IV) (P = 0.017), primary site (oro-hypopharynx) (P = 0.041) and radiation portal size (> 11 cm) (P < 0.001) were found to be associated with severe dysphagia. In multivariate analysis, only radiation portal size was found to have a significant relationship with severe dysphagia (P = 0.048). Larger radiation portal field was associated with severe dysphagia induced by chemoradiotherapy. | |||||
資源タイプ(コンテンツの種類) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0368-2811 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00690866 | |||||
PubMed | ||||||
識別子タイプ | PMID | |||||
関連識別子 | https://pubmed.ncbi.nlm.nih.gov/19383615 | |||||
関連名称 | 19383615 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1093/jjco/hyp033 | |||||
関連名称 | 10.1093/jjco/hyp033 | |||||
権利 | ||||||
権利情報 | Copyright© The Author 2009. Published by Oxford University Press. | |||||
権利 | ||||||
権利情報 | This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Jpn. J. Clin. Oncol. following peer review. The definitive publisher-authenticated version Jpn. J. Clin. Oncol. (2009) 39 (7): 413-417 is available online at: doi: 10.1093/jjco/hyp033 | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
WoS | ||||||
表示名 | Web of Science | |||||
URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000267441600001 |