@article{oai:soar-ir.repo.nii.ac.jp:00003832, author = {Kasuga, Eriko and Kawakami, Yoshiyuki and Matsumoto, Takehisa and Hidaka, Eiko and Oana, Kozue and Ogiwara, Naoko and Yamaki, Dai and Sakurada, Tsukasa and Honda, Takayuki}, journal = {INTERNATIONAL JOURNAL OF NANOMEDICINE}, month = {}, note = {Background: Bacteria from the hospital environment, including linens and curtains, are often responsible for hospital-associated infections. The aim of the present study was to evaluate the bactericidal effects of fabrics coated with the hydroxyapatite-binding silver/titanium dioxide ceramic nanocomposite "Earth-plus". Methods: Bactericidal activities of woven and nonwoven fabrics coated with Earth-plus were investigated by the time-kill curve method using nine bacterial strains, including three Staphylococcus aureus, three Escherichia coli, and three Pseudomonas aeruginosa strains. Results: The numbers of viable S. aureus and E. coli cells on both fabrics coated with Earth-plus decreased to below 2 log(10) colony-forming units/mL in six hours and reached the detection limit in 18 hours. Viable cell counts of P. aeruginosa on both fabrics coated with Earth-plus could not be detected after 3-6 hours. Viable cells on woven fabrics showed a more rapid decline than those on nonwoven fabrics. Bacterial cell counts of the nine strains on fabrics without Earth-plus failed to decrease even after 18 hours. Conclusion: Woven cotton and nonwoven polypropylene fabrics were shown to have excellent antibacterial potential. The woven fabric was more bactericidal than the nonwoven fabric., Article, INTERNATIONAL JOURNAL OF NANOMEDICINE. 6:1937-1943 (2011)}, pages = {1937--1943}, title = {Bactericidal activities of woven cotton and nonwoven polypropylene fabrics coated with hydroxyapatite-binding silver/titanium dioxide ceramic nanocomposite "Earth-plus"}, volume = {6}, year = {2011} }