{"created":"2021-03-01T06:07:41.124564+00:00","id":3852,"links":{},"metadata":{"_buckets":{"deposit":"a2d25ed4-4e38-4bfd-a208-10c0f151ba8f"},"_deposit":{"id":"3852","owners":[],"pid":{"revision_id":0,"type":"depid","value":"3852"},"status":"published"},"_oai":{"id":"oai:soar-ir.repo.nii.ac.jp:00003852","sets":["461:462"]},"author_link":["7529","7530","7531","7532","7533"],"item_1628147817048":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"425","bibliographicPageStart":"421","bibliographicVolumeNumber":"58","bibliographic_titles":[{"bibliographic_title":"EXPERIMENTAL ANIMALS"}]}]},"item_6_description_20":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Genetic alterations in the gene for ATP-binding cassette, sub-family B (MDR/TAP), member 1A (ABCB1A) determine susceptibility to colitis in mice and humans. We investigated the influence of ABCB1A dysfunction on susceptibility to dextran sulfate sodium (DSS)-induced colitis by using Senescence-Accelerated Mouse (SAM) strains with a loss-of-function mutation in the Abcb1a gene (SAMR1, SAMP1, and SAMP6). Susceptibility to DSS colitis was different among SAM strains but on the whole was not different from other mouse strains with normal ABCB1A function. Thus, genetic factors other than loss of ABCB1A are more crucial in determining susceptibility to DSS colitis in SAM strains.","subitem_description_type":"Abstract"}]},"item_6_description_30":{"attribute_name":"資源タイプ（コンテンツの種類）","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_6_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"EXPERIMENTAL ANIMALS. 58(4):421-425 (2009)","subitem_description_type":"Other"}]},"item_6_link_3":{"attribute_name":"信州大学研究者総覧へのリンク","attribute_value_mlt":[{"subitem_link_text":"Higuchi, Keiichi","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.gCfUPmAh.html"},{"subitem_link_text":"Mori, Masayuki","subitem_link_url":"http://soar-rd.shinshu-u.ac.jp/profile/ja.OpSCZafV.html"}]},"item_6_link_67":{"attribute_name":"WoS","attribute_value_mlt":[{"subitem_link_url":"http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000268442400012"}]},"item_6_publisher_4":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Association for Laboratory Animal Science"}]},"item_6_relation_47":{"attribute_name":"PubMed","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"19654441"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pubmed.ncbi.nlm.nih.gov/19654441","subitem_relation_type_select":"PMID"}}]},"item_6_relation_48":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"10.1538/expanim.58.421"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1538/expanim.58.421","subitem_relation_type_select":"DOI"}}]},"item_6_rights_62":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2009 Japanese Association for Laboratory Animal Science"}]},"item_6_source_id_35":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-1357","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_40":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11032321","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Zhang,  Guohong","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fu,  Xiaoying","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeda,  Toshio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Higuchi,  Keiichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mori,  Masayuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-24"}],"displaytype":"detail","filename":"Dysfunction_ABCB1A_Has_Only_Weak_Effect.pdf","filesize":[{"value":"424.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Dysfunction_ABCB1A_Has_Only_Weak_Effect.pdf","url":"https://soar-ir.repo.nii.ac.jp/record/3852/files/Dysfunction_ABCB1A_Has_Only_Weak_Effect.pdf"},"version_id":"30976074-2209-4caa-bce5-6e14f19bb8d7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ABCB1A","subitem_subject_scheme":"Other"},{"subitem_subject":"dextran sulfate sodium-induced colitis","subitem_subject_scheme":"Other"},{"subitem_subject":"Senescence-Accelerated Mouse","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Dysfunction in ABCB1A Has Only a Weak Effect on Susceptibility to Dextran Sulfate Sodium-Induced Colitis in SAM Strains","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dysfunction in ABCB1A Has Only a Weak Effect on Susceptibility to Dextran Sulfate Sodium-Induced Colitis in SAM Strains","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["462"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-10-11"},"publish_date":"2011-10-11","publish_status":"0","recid":"3852","relation_version_is_last":true,"title":["Dysfunction in ABCB1A Has Only a Weak Effect on Susceptibility to Dextran Sulfate Sodium-Induced Colitis in SAM Strains"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-14T04:39:58.619930+00:00"}