@article{oai:soar-ir.repo.nii.ac.jp:00003855,
 author = {Tsukahara,  Tamotsu and Haniu,  Hisao},
 issue = {4},
 journal = {BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS},
 month = {Mar},
 note = {In this report, we sought to elucidate whether multiwall carbon nanotubes are involved in the modulation of the proliferation and differentiation of the skeletal muscle cell line C2C12. Skeletal muscle is a major mass peripheral tissue that accounts for 40% of total body weight and 50% of energy consumption. We focused on the differentiation pathway of myoblasts after exposure to a vapor-grown carbon fiber, HTT2800, which is one of the most highly purified carbon nanotubes. This treatment leads in parallel to the expression of a typical adipose differentiation program. We found that HTT2800 stimulated intracellular lipid accumulation in C2C12 cells. We have also shown by quantified PCR analysis that the expression of adipose-related genes was markedly upregulated during HTT2800 exposure. Taken together, these results suggest that HTT2800 specifically converts the differentiation pathway of C2C12 myoblasts to that of adipoblast-like cells., Article, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 406(4):558-563 (2011)},
 pages = {558--563},
 title = {Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation},
 volume = {406},
 year = {2011}
}