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  1. 050 医学部, 大学院医学系研究科
  2. 0501 学術論文

Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases

http://hdl.handle.net/10091/11109
http://hdl.handle.net/10091/11109
644d990e-5c89-4a23-8e23-dbb1a8cb5f6a
名前 / ファイル ライセンス アクション
Genetic_basis_inter-individual_variability.pdf Genetic_basis_inter-individual_variability.pdf (547.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2011-01-20
タイトル
タイトル Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases
言語
言語 eng
DOI
関連識別子 https://doi.org/10.1113/jphysiol.2009.179283
関連名称 10.1113/jphysiol.2009.179283
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Mori, Masayuki

× Mori, Masayuki

en Mori, Masayuki

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Higuchi, Keiichi

× Higuchi, Keiichi

en Higuchi, Keiichi

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Sakurai, Akihiro

× Sakurai, Akihiro

en Sakurai, Akihiro

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Tabara, Yasuharu

× Tabara, Yasuharu

en Tabara, Yasuharu

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Miki, Tetsuro

× Miki, Tetsuro

en Miki, Tetsuro

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Nose, Hiroshi

× Nose, Hiroshi

en Nose, Hiroshi

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信州大学研究者総覧へのリンク
氏名 Mori, Masayuki
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.OpSCZafV.html
信州大学研究者総覧へのリンク
氏名 Higuchi, Keiichi
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.gCfUPmAh.html
信州大学研究者総覧へのリンク
氏名 Nose, Hiroshi
URL http://soar-rd.shinshu-u.ac.jp/profile/ja.HUyVuUkh.html
出版者
出版者 WILEY-BLACKWELL PUBLISHING, INC
引用
内容記述 JOURNAL OF PHYSIOLOGY-LONDON. 587(23):5577-5584 (2009)
書誌情報 JOURNAL OF PHYSIOLOGY-LONDON

巻 587, 号 23, p. 5577-5584, 発行日 2009-12
内容記述
内容記述タイプ Other
内容記述 The definitive version is available at www.blackwell-synergy.com and www.jphysiol.org .
抄録
内容記述 Habitual exercise training, including a high-intensity interval walking programme, improves cardiorespiratory fitness and alleviates lifestyle-related diseases, such as obesity, hypertension and dyslipidaemia. However, the extent of improvement has been shown to differ substantially among individuals for various exercise regimens. A body of literature has demonstrated that gene polymorphisms could account for the inter-individual variability in the improvement of risk factors for lifestyle-related diseases following exercise training. However, the fractions of the variability explained by the polymorphisms are small (similar to 5%). Also, it is likely that the effects of gene polymorphisms differ with exercise regimens and subject characteristics. These observations suggest the necessity for further studies to exhaustively identify such gene polymorphisms. More importantly, the physiological and molecular genetic mechanisms by which gene polymorphisms interact with exercise to influence the improvements of risk factors for lifestyle-related diseases differentially remain to be clarified. A better understanding of these issues should lead to more effective integration of exercise to optimize the treatment and management of individuals with lifestyle-related diseases.
資源タイプ(コンテンツの種類)
ISSN
収録物識別子タイプ PISSN
収録物識別子 0022-3751
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00253169
PubMed
識別子タイプ PMID
関連識別子 https://pubmed.ncbi.nlm.nih.gov/19736300
関連名称 19736300
権利
権利情報 Copyright (c) 2009 The Physiological Society
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
WoS
URL http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000272307800015
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Cite as

Mori, Masayuki, Higuchi, Keiichi, Sakurai, Akihiro, Tabara, Yasuharu, Miki, Tetsuro, Nose, Hiroshi, 2009, Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases: WILEY-BLACKWELL PUBLISHING, INC, 5577–5584 p.

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