{"_buckets": {"deposit": "cea0bb35-6d8d-46f1-92f6-518fcd70f8c6"}, "_deposit": {"id": "3859", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "3859"}, "status": "published"}, "_oai": {"id": "oai:soar-ir.repo.nii.ac.jp:00003859", "sets": ["462"]}, "author_link": ["7571", "7572", "7573", "7574", "7575", "7576"], "item_1628147817048": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "23", "bibliographicPageEnd": "5584", "bibliographicPageStart": "5577", "bibliographicVolumeNumber": "587", "bibliographic_titles": [{"bibliographic_title": "JOURNAL OF PHYSIOLOGY-LONDON"}]}]}, "item_6_description_19": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "The definitive version is available at www.blackwell-synergy.com and www.jphysiol.org .", "subitem_description_type": "Other"}]}, "item_6_description_20": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Habitual exercise training, including a high-intensity interval walking programme, improves cardiorespiratory fitness and alleviates lifestyle-related diseases, such as obesity, hypertension and dyslipidaemia. However, the extent of improvement has been shown to differ substantially among individuals for various exercise regimens. A body of literature has demonstrated that gene polymorphisms could account for the inter-individual variability in the improvement of risk factors for lifestyle-related diseases following exercise training. However, the fractions of the variability explained by the polymorphisms are small (similar to 5%). Also, it is likely that the effects of gene polymorphisms differ with exercise regimens and subject characteristics. These observations suggest the necessity for further studies to exhaustively identify such gene polymorphisms. More importantly, the physiological and molecular genetic mechanisms by which gene polymorphisms interact with exercise to influence the improvements of risk factors for lifestyle-related diseases differentially remain to be clarified. A better understanding of these issues should lead to more effective integration of exercise to optimize the treatment and management of individuals with lifestyle-related diseases.", "subitem_description_type": "Abstract"}]}, "item_6_description_30": {"attribute_name": "資源タイプ（コンテンツの種類）", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_6_description_31": {"attribute_name": "フォーマット：mimeタイプ", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_6_description_5": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "JOURNAL OF PHYSIOLOGY-LONDON. 587(23):5577-5584 (2009)", "subitem_description_type": "Other"}]}, "item_6_link_3": {"attribute_name": "信州大学研究者総覧へのリンク", "attribute_value_mlt": [{"subitem_link_text": "Mori, Masayuki", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.OpSCZafV.html"}, {"subitem_link_text": "Higuchi, Keiichi", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.gCfUPmAh.html"}, {"subitem_link_text": "Nose, Hiroshi", "subitem_link_url": "http://soar-rd.shinshu-u.ac.jp/profile/ja.HUyVuUkh.html"}]}, "item_6_link_67": {"attribute_name": "WoS", "attribute_value_mlt": [{"subitem_link_text": "Web of Science", "subitem_link_url": "http://gateway.isiknowledge.com/gateway/Gateway.cgi?\u0026GWVersion=2\u0026SrcAuth=ShinshuUniv\u0026SrcApp=ShinshuUniv\u0026DestLinkType=FullRecord\u0026DestApp=WOS\u0026KeyUT=000272307800015"}]}, "item_6_publisher_4": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "WILEY-BLACKWELL PUBLISHING, INC"}]}, "item_6_relation_47": {"attribute_name": "PubMed", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "19736300"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://pubmed.ncbi.nlm.nih.gov/19736300", "subitem_relation_type_select": "PMID"}}]}, "item_6_relation_48": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1113/jphysiol.2009.179283"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1113/jphysiol.2009.179283", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_62": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright (c) 2009 The Physiological Society"}]}, "item_6_select_64": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_6_source_id_35": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-3751", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_39": {"attribute_name": "NII ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-3751", "subitem_source_identifier_type": "PISSN"}]}, "item_6_source_id_40": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00253169", "subitem_source_identifier_type": "NCID"}]}, "item_6_text_70": {"attribute_name": "wosonly keywords", "attribute_value_mlt": [{"subitem_text_value": "GENOME-WIDE ASSOCIATION; ANGIOTENSIN-CONVERTING-ENZYME; BODY-MASS INDEX; PHYSICAL-ACTIVITY; BLOOD-PRESSURE; CARDIORESPIRATORY FITNESS; HERITAGE FAMILY; INSULIN SENSITIVITY; SUBCUTANEOUS FAT; POLYMORPHISM"}]}, "item_6_textarea_68": {"attribute_name": "wosonly abstract", "attribute_value_mlt": [{"subitem_textarea_value": "Habitual exercise training, including a high-intensity interval walking programme, improves cardiorespiratory fitness and alleviates lifestyle-related diseases, such as obesity, hypertension and dyslipidaemia. However, the extent of improvement has been shown to differ substantially among individuals for various exercise regimens. A body of literature has demonstrated that gene polymorphisms could account for the inter-individual variability in the improvement of risk factors for lifestyle-related diseases following exercise training. However, the fractions of the variability explained by the polymorphisms are small (similar to 5%). Also, it is likely that the effects of gene polymorphisms differ with exercise regimens and subject characteristics. These observations suggest the necessity for further studies to exhaustively identify such gene polymorphisms. More importantly, the physiological and molecular genetic mechanisms by which gene polymorphisms interact with exercise to influence the improvements of risk factors for lifestyle-related diseases differentially remain to be clarified. A better understanding of these issues should lead to more effective integration of exercise to optimize the treatment and management of individuals with lifestyle-related diseases."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Mori,  Masayuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7571", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Higuchi,  Keiichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7572", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakurai,  Akihiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7573", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tabara,  Yasuharu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7574", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miki,  Tetsuro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7575", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nose,  Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7576", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2015-09-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Genetic_basis_inter-individual_variability.pdf", "filesize": [{"value": "547.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 547500.0, "url": {"label": "Genetic_basis_inter-individual_variability.pdf", "url": "https://soar-ir.repo.nii.ac.jp/record/3859/files/Genetic_basis_inter-individual_variability.pdf"}, "version_id": "d10697cd-5aed-46bb-bc39-502d006310ef"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["462"], "permalink_uri": "http://hdl.handle.net/10091/11109", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2011-01-20"}, "publish_date": "2011-01-20", "publish_status": "0", "recid": "3859", "relation": {}, "relation_version_is_last": true, "title": ["Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases"], "weko_shared_id": -1}