@article{oai:soar-ir.repo.nii.ac.jp:00003867,
 author = {Joshita,  Satoru and Nakazawa,  Koh and Koike,  Shoichiro and Kamijo,  Atsushi and Matsubayashi,  Kiyoshi and Miyabayashi,  Hideharu and Furuta,  Kiyoshi and Kitano,  Kiyoshi and Yoshizawa,  Kaname and Tanaka,  Eiji},
 issue = {3},
 journal = {JOURNAL OF KOREAN MEDICAL SCIENCE},
 month = {Oct},
 note = {Granulocyte-colony stimulating factor (G-CSF) is a naturally occurring glycoprotein that stimulates the proliferation and maturation of precursor cells in the bone marrow into fully differentiated neutrophils. Several reports of G-CSF-producing malignant tumors have been published, but scarcely any in the hepatobiliary system, such as in hepatocellular carcinoma (HCC). Here, we encountered a 69-yr-old man with a hepatic tumor who had received right hepatic resection. He showed leukocytosis of 25,450/mL along with elevated serum G-CSF. Histological examination of surgical samples demonstrated immunohistochemical staining for G-CSF, but not for G-CSF receptor. The patient survived without recurrence for four years, but ultimately passed away with multiple bone metastases. In light of the above, clinicians may consider G-CSF-producing HCC when encountering patients with leukocytosis and a hepatic tumor. More cases are needed to clarify the clinical picture of G-CSF-producing HCC., http://jkms.org/ | http://jkms.org/, Article, JOURNAL OF KOREAN MEDICAL SCIENCE. 25(3):476-480 (2010)},
 pages = {476--480},
 title = {A Case of Granulocyte-Colony Stimulating Factor-Producing Hepatocellular Carcinoma Confirmed by Immunohistochemistry},
 volume = {25},
 year = {2010}
}