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Non-thermal cytocidal effect of infrared irradiation on cultured cancer cells using specialized device
http://hdl.handle.net/10091/11074
http://hdl.handle.net/10091/110741304962e-3191-4597-8e97-0302bac320f2
| 名前 / ファイル | ライセンス | アクション |
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Non-thermal_cytocidal_effect_infrared_irradiation.pdf (1.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2011-01-13 | |||||
| タイトル | ||||||
| タイトル | Non-thermal cytocidal effect of infrared irradiation on cultured cancer cells using specialized device | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| DOI | ||||||
| 関連識別子 | https://doi.org/10.1111/j.1349-7006.2010.01548.x | |||||
| 関連名称 | 10.1111/j.1349-7006.2010.01548.x | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Tanaka, Yohei
× Tanaka, Yohei× Matsuo, Kiyoshi× Yuzuriha, Shunsuke× Yan, Huimin× Nakayama, Jun |
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| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Yuzuriha, Shunsuke | |||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.gULNHhkh.html | |||||
| 信州大学研究者総覧へのリンク | ||||||
| 表示名 | Nakayama, Jun | |||||
| URL | http://soar-rd.shinshu-u.ac.jp/profile/ja.HCApHFkh.html | |||||
| 出版者 | ||||||
| 出版者 | WILEY-BLACKWELL PUBLISHING, INC | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | CANCER SCIENCE. 101(6):1396-1402 (2010) | |||||
| 書誌情報 |
CANCER SCIENCE 巻 101, 号 6, p. 1396-1402, 発行日 2010-06 |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The definitive version is available at www.blackwell-synergy.com | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | As infrared penetrates the skin, thermal effects of infrared irradiation on cancer cells have been investigated in the field of hyperthermia. We evaluated non-thermal effects of infrared irradiation using a specialized device (1100-18000 nm with filtering of wavelengths between 1400 and 1500 nm and contact cooling) on cancer cells. In in vitro study, five kinds of cultured cancer cell lines (MCF7 breast cancer, HeLa uterine cervical cancer, NUGC-4 gastric cancer, B16F0 melanoma, and MDA-MB435 melanoma) were irradiated using the infrared device, and then the cell proliferation activity was evaluated by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. Proliferation of all the cancer cell lines was significantly suppressed by infrared irradiation. Total infrared output appeared to be correlated with cell survival. Increased temperature during infrared irradiation appeared not to play a role in cell survival. The maximum temperature elevation in the wells after each shot in the 20 and 40 J/cm2 culture was 3.8 degrees C and 6.9 degrees C, respectively. In addition, we have shown that infrared irradiation significantly inhibited the tumor growth of MCF7 breast cancer transplanted in severe combined immunodeficiency mice and MDA-MB435 melanoma transplanted in nude mice in vivo. Significant differences between control and irradiated groups were observed in tumor volume and frequencies of TUNEL-positive and Ki-67-positive cells. These results indicate that infrared, independent of thermal energy, can induce cell killing of cancer cells. As this infrared irradiation schedule reduces discomfort and side effects, reaches the deep subcutaneous tissues, and facilitates repeated irradiations, it may have potential as an application for treating various forms of cancer. | |||||
| 資源タイプ（コンテンツの種類） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1347-9032 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11808050 | |||||
| PubMed | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | https://pubmed.ncbi.nlm.nih.gov/20345484 | |||||
| 関連名称 | 20345484 | |||||
| 権利 | ||||||
| 権利情報 | Copyright (c) 2010 Japanese Cancer Association | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| WoS | ||||||
| 表示名 | Web of Science | |||||
| URL | http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=ShinshuUniv&SrcApp=ShinshuUniv&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000277913800010 | |||||
