@article{oai:soar-ir.repo.nii.ac.jp:00003931, author = {Uhara, H and Baba, A and Shiohara, J and Saida, T}, issue = {5}, journal = {Journal of American Academy of Dermatology}, month = {May}, note = {We report a male infant with Down syndrome who had a transient myeloproliferative disorder associated with skin lesions. He was transferred to a neonatal intensive care unit because of low body weight, fetal edema, disseminated intravascular coagulation, and 10% blast cells in the peripheral blood. On postnatal day (PD) 1, erythema with small papules, vesicles, and pustules appeared on the entire body. A smear preparation from the pustules on PD 2 showed 10% blast cells. A biopsy specimen taken on PD 5 revealed subcorneal pustules containing neutrophils and eosinophils. Genetic analyses detected a somatic mutation (197G>T, Glu295Stop) in exon 2 of GATA-1. On PD 10, the eruptions resolved spontaneously and the population of blast cells in peripheral blood decreased to 1%. The number of blast cells in pustules decreased markedly after three days. Therefore, we recommend that cytologic examination should be performed as early as possible., Article, Journal of American Academy of Dermatology. 60(5):869-871 (2009)}, pages = {869--871}, title = {Transient myeloproliferative disorder with vesiculopustular eruption: Early smear is useful for quick diagnosis}, volume = {60}, year = {2009} }