@article{oai:soar-ir.repo.nii.ac.jp:00004137, author = {家里, 明日美 and 春日, 好雄 and 原田, 道彦 and 上原, 剛}, issue = {3}, journal = {信州医学雑誌}, month = {Jun}, note = {Medullary thyroid carcinoma (MTC) is a relatively rare phenomenon. We report three cases of MTC over the past 14years in our department. Two cases were determined out by hypercarcinoembryonic antigenemia, and one by hypercarcinoembryonic antigenemia and abnormal uptake by fluorodeoxyglucose-positron emission tomography (FDG-PET) examination. The serum calcitonin level was high in each of the three cases. It was difficult to diagnose MTC by imaging findings or fine needle aspiration in our cases. We diagnosed sporadic MTC in these cases by family history and endocrinological findings. Thyroid lobectomy was performed in one case, and subtotal thyroidectomy in two cases because of concomitant denomatous goiter in the contralateral thyroid lobe. The preoperative calcitonin-to-carcinoembryonic antigen (CEA) ratio seems to be useful as a prognostic factor. As the ratios in our cases were above 10, their prognosis will be good. A strict follow-up study is nessesary., Article, 信州医学雑誌 60(3): 85-91(2012)}, pages = {157--161}, title = {当科で経験した甲状腺髄様癌の3例}, volume = {60}, year = {2012} }